Outcome of Endoscopic Sinus Surgery in Patients with Symptomatic Chronic Rhinosinusitis with Minimal Changes on Computerised Tomography
Outcome of Endoscopic Sinus Surgery in Patients with Symptomatic Chronic Rhinosinusitis with Minimal Changes on Computerised Tomography
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DOI：
10.1007/s12070-011-0278-7
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发表时间：
2011-06
影响因子：
0.6
通讯作者：
A. Chakravarti;S. Naglot;R. Dhawan
中科院分区：
文献类型：
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作者：
A. Chakravarti;S. Naglot;R. Dhawan
本研究旨在评估功能性内窥镜鼻窦手术（FESS）在影像学检查结果极轻微的慢性鼻窦炎（CRS）患者中的疗效，并基于在新德里Hardinge夫人医学院耳鼻喉科进行的一项中心前瞻性随机对照研究。所有CRS门诊患者（>18岁）对3周的药物治疗无效，进行鼻和鼻窦计算机断层扫描（CT）的放射学评估。根据CT评分（隆德Mackay分期系统）将这些患者分组：A组（CT评分0-6）和B组（CT评分7-24）;每组35例患者。所有患者均采用Messerklinger技术行FESS。所有患者在术前和术后1、3、6和12个月随访时使用视觉模拟量表进行症状评分。CRS患者在CT上有轻微的疾病证据，FESS后症状评分有统计学显著改善。两组的总体症状评分改善以及特定症状改善无显著差异。此外，术前症状与CT评分之间无相关性。在CT显示疾病证据最少的CRS患者中，FESS可以获得症状改善方面的良好主观结局。
This study was designed to assess the efficacy of functional endoscopic sinus surgery (FESS) in chronic rhinosinusitis (CRS) patients with minimal radiological findings, and based on one centre, prospective randomized controlled study, conducted in the Department of Otorhinolaryngology, Lady Hardinge Medical College, New Delhi. All the CRS out-patients (>18 years) refractory to 3 weeks of medical therapy were radiologically evaluated with computerised tomographic scan (CT) of nose and paranasal sinuses. These patients were grouped based on CT scoring (Lund Mackay staging system): group A (CT score 0–6) and group B (CT score 7–24); with 35 patients in each group. All the patients underwent FESS using Messerklinger technique. Symptom scoring of all the patients was done using visual analog scale preoperatively and postoperatively at 1-, 3-, 6- and 12-month follow-up. CRS patients with minimal evidence of disease on CT showed statistically significant improvement in symptom scores after FESS. There was no significant difference noted in the overall symptom score improvement as well as for improvement in specific symptoms in both the groups. Further, there was no correlation between the pre-operative symptoms and CT scores. A good subjective outcome in terms of symptom improvement can be obtained with FESS in patients with CRS with minimal evidence of disease on CT.