Effects of differential environments on plasticity of dendrites of cortical pyramidal neurons in adult rats
Effects of differential environments on plasticity of dendrites of cortical pyramidal neurons in adult rats
复制标题
不同环境对成年大鼠皮质锥体神经元树突可塑性的影响
DOI：
10.1016/0014-4886(78)90276-5
复制
发表时间：
1978
影响因子：
5.3
通讯作者：
W. Veltman
中科院分区：
文献类型：
--
作者：
H. Uylings;K. Kuypers;M. Diamond;W. Veltman
在暴露于“强化”状态后，在成年后观察到额叶皮质，尤其是枕叶皮质增厚。在“标准”和“强化”条件下，视皮层第II层和第III层锥体细胞的树突分支和终末节段长度增加。这些暴露从第112天开始，持续30天。浅层锥体细胞的树突状细胞在富集化条件下的增加明显大于标准条件下。此外，分枝似乎主要发生在距顶端相当远的所有目的基端节段上。这种生长模式类似于在正常未成熟大鼠的皮质中观察到的模式。微分条件对分岔角没有影响。文献中报道的树突和皮质的变化和变化表明，不同经验的影响并不局限于一段短暂的“关键”时期。
Thickening of the frontal cortex and especially the occipital cortex was observed inadultrats after exposure to the “enriched” condition. An increase in branching and in length of terminal segments was found in the dendritic tree of pyramidal cells in layers II and III of the visual cortex of theadultrat after exposure to “standard” and enriched conditions. These exposures began at day 112 and continued 30 days. The increase observed in the basal dendritic tree of pyramidal cells in the superficial layers was significantly greater in the enriched conditions than in the standard condition. It appeared, furthermore, that branching occurred predominantly on basal terminal segments of all orders at a considerable distance from the tip. This mode of growth is similar to that observed in the cortex of normal immature rats. The differential conditions did not influence the bifurcation angles. The dendritic and cortical changes and changes reported in the literature indicate that the effects of differential experience are not limited to a short, “critical” period.