Specular microscopy of irido-corneal endothelial syndrome.
Specular microscopy of irido-corneal endothelial syndrome.
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虹膜角膜内皮综合征的镜面显微镜。
DOI：
10.1111/j.1442-9071.1980.tb01672.x
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Shields,NB
中科院分区：
文献类型：
--
作者：
Hirst,LW;Quigley,HA;Stark,WJ;Shields,NB
对17例具有虹膜-角膜内皮综合征（包括钱德勒综合征、虹膜痣综合征和原发性虹膜萎缩）共同特征的患者进行了临床镜下检查，发现了典型的内皮改变，没有正常的内皮马赛克区域。即使在那些有轻微前粘连的患者中，也可以发现明显的中央内皮改变，这表明内皮改变是原发性的，而不是继发于虹膜-角膜粘连。患者临床未受累的对侧眼的镜面显微镜显示内皮细胞多形性与患者年龄不相称。本研究也证实了镜面显微镜在内皮细胞定性观察中的价值。
Clinical specular microscopic examination of 17 patients with features common to the irido‐corneal endothelial syndrome (including Chandler's syndrome, iris nevus syndrome, and essential iris atrophy) revealed pathognomonic endothelial changes and no areas of normal endothelial mosaic. Even in those patients with minimal anterior synechiae, gross central endothelial changes could be found, suggesting that the endothelial changes are primary and not secondary to the iris‐corneal adhesions. Specular microscopy of the clinically‐uninvolved contralateral eye in the patients revealed frequent endothelial‐cell pleomorphism incommensurate with the patient's age. This study also confirmed the value of the specular microscope in making qualitative endothelial observations.