ANAEROBIC BACTERIAL-INFECTIONS OF THE LUNG AND PLEURAL SPACE
ANAEROBIC BACTERIAL-INFECTIONS OF THE LUNG AND PLEURAL SPACE
复制标题
DOI：
10.1093/clinids/16.supplement_4.s248
复制
发表时间：
1993-06-01
影响因子：
11.8
通讯作者：
BARTLETT, JG
中科院分区：
文献类型：
--
作者：
BARTLETT, JG
在193例涉及厌氧菌的胸膜肺感染病例中，主要临床症状为吸入性肺炎、肺脓肿和脓胸。大多数患者在最初出现时有迟发性感染并伴有组织坏死(脓肿或支气管肺瘘)。然而，许多人的病程更猛烈，类似于肺炎球菌肺炎。经气管抽吸是最常用的获得无污染标本进行厌氧培养的程序；由于目前很少使用该程序，因此厌氧菌引起的肺部感染目前很少有病原学诊断。主要病原菌为消化链球菌、类杆菌、普氏杆菌和梭杆菌。虽然克林霉素被广泛认为是首选抗生素，但适当的治疗试验可能会证明许多抗生素对厌氧胸膜肺感染是有效的。
In 193 reviewed cases of pleuropulmonary infections involving anaerobic bacteria, the predominant clinical syndromes were aspiration pneumonia, lung abscess, and empyema. Most patients had an indolent infection with tissue necrosis (abscess or bronchopulmonary fistula) at initial presentation. Nevertheless, many had a more fulminant disease course resembling that of pneumococcal pneumonia. Transtracheal aspiration was the procedure most commonly used to obtain uncontaminated specimens for anaerobic culture; since this procedure now is seldom employed, pulmonary infections due to anaerobes rarely have an etiologic diagnosis at present. The dominant pathogens are Peptostreptococcus, Bacteroides, Prevotella, and Fusobacterium species. Although clindamycin is widely considered to be the antibiotic of choice, proper therapeutic trials would probably prove many antibiotics to be effective for the treatment of anaerobic pleuropulmonary infections.