Gating-ML: XML-Based Gating Descriptions in Flow Cytometry
Gating-ML: XML-Based Gating Descriptions in Flow Cytometry
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DOI：
10.1002/cyto.a.20637
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发表时间：
2008-12-01
期刊：
影响因子：
3.7
通讯作者：
Brinkman, Ryan R.
中科院分区：
文献类型：
--
作者：
Spidlen, Josef;Leif, Robert C.;Brinkman, Ryan R.
由于缺乏用于数据交换的标准化机制而导致的关于门控的软件互操作性的缺乏在传统上一直是瓶颈，从而阻止流式细胞术（FCM）数据分析的再现性和多种分析工具的使用。为了促进FCM数据分析工具之间的互操作性，国际细胞计数促进协会（ISAC）数据标准工作组（DSTF）的成员开发了一种基于XML的机制来正式描述门（Gating-ML）。Gating-ML是一种用于编码门控、数据转换和补偿的开放规范，已被ISAC DSTF作为候选建议采纳。Gating-ML可以促进门控描述的交换，就像FCS促进原始FCM数据的交换一样。它的采用将开辟新的合作机会，以及先进的分析和方法开发的可能性。ISAC DSTF认为该标准满足门控交换标准的要求。(C)2008年国际细胞计数促进学会
The lack of software interoperability with respect to gating due to lack of a standardized mechanism for data exchange has traditionally been a bottleneck, preventing reproducibility of flow cytometry (FCM) data analysis and the usage of multiple analytical tools. To facilitate interoperability among FCM data analysis tools, members of the International Society for the Advancement of Cytometry (ISAC) Data Standards Task Force (DSTF) have developed an XML-based mechanism to formally describe gates (Gating-ML). Gating-ML, an open specification for encoding gating, data transformations and compensation, has been adopted by the ISAC DSTF as a Candidate Recommendation. Gating-ML can facilitate exchange of gating descriptions the same way that FCS facilitated for exchange of raw FCM data. Its adoption will open new collaborative opportunities as well as possibilities for advanced analyses and methods development. The ISAC DSTF is satisfied that the standard addresses the requirements for a gating exchange standard.(C) 2008 international Society for Advancement of Cytometry