Homotransplantation of the kidney in the human.
Homotransplantation of the kidney in the human.
复制标题
人类同种异体肾脏移植。
DOI：
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发表时间：
1950
影响因子：
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通讯作者：
R. P. Murphy
中科院分区：
文献类型：
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作者：
R. H. Lawler;J. West;P. McNulty;E. Clancy;R. P. Murphy
自体移植物和同种移植物的移植长期以来一直占据着许多工作者的努力。Williamson在1923年和1926年专门报道了肾脏同种移植。虽然肾脏移植从未在人类身上进行过尝试，但在实验动物身上同种移植物的命运是相当众所周知的。Markowitz 3在他关于器官移植的讨论中提出了一些结论，表明宿主和供体的相似性越大，移植越成功。弗莱舍已经证明，眼睛的晶状体很容易移植（通过植入），而且它不会被吞噬细胞侵入。曼恩、马科维茨和他的同事们在同种移植的完整哺乳动物心脏中发现，这个器官的功能可以维持8天之久，但肌肉最终会被吞噬细胞填满，停止功能。根据这些工人的说法，
The transplantation of both autogenous and homogenous grafts has long occupied the efforts of many workers. Williamson reported specifically on renal homotransplantation in 1923 1 and again in 1926. 2 Although the renal transplant has never before been attempted in the human, the fate of homogenous grafts in laboratory animals is fairly well known. Markowitz 3 in his discussion of the transplantation of organs presents certain conclusions which show that the greater the similarity of host and donor the more successful is the grafting. Fleisher 4 has shown that the lens of the eye is readily transplantable (by implantation) and that it does not become invaded by phagocytes. Mann, Markowitz and associates 5 have shown in homotransplants of the intact mammalian heart that the organ will function for as long as eight days but that the muscle finally becomes riddled with phagocytes and ceases to function. According to these workers,