P3-LIKE BRAIN WAVES IN NORMAL MONKEYS AND IN MONKEYS WITH MEDIAL TEMPORAL LESIONS
P3-LIKE BRAIN WAVES IN NORMAL MONKEYS AND IN MONKEYS WITH MEDIAL TEMPORAL LESIONS
复制标题
DOI：
10.1037/0735-7044.102.5.714
复制
发表时间：
1988-10-01
影响因子：
1.9
通讯作者：
HILLYARD, SA
中科院分区：
文献类型：
--
作者：
PALLER, KA;ZOLAMORGAN, S;HILLYARD, SA
人类大脑会对意外发生的相关事件产生特有的电反应。最近的报告表明，这种与事件相关的脑电位的一个重要部分--P3波--可能与记忆功能有关，并且可能源于内侧颞叶（尤其是海马体）内的活动。后一种想法通过对猴子脑电波的硬膜外记录进行了测试。异常听觉刺激的反应与人类受试者在可比条件下记录的P3波非常相似。双侧内侧颞叶病变的猴子仍然产生P3样脑电波，这表明内侧颞叶脑结构对它们的产生并不重要。
The human brain produces a characteristic electrical response to relevant events that occur unexpectedly. Recent reports have suggested that a prominent part of this event-related brain potential-the P3 wave-may be related to memory functions and may arise from activity within the medial temporal lobe, especially the hippocampus. The latter idea was tested by means of epidural recordings of brain waves in monkeys. Responses to deviant auditory stimuli bore a close resemblance to P3 waves recorded from human subjects under comparable conditions. Monkeys with bilateral lesions of the medial temporal lobe still produced P3-like brain waves, which indicates that medial temporal brain structures are not critical for their generation.