Trends in inflammatory breast carcinoma incidence and survival: The Surveillance, Epidemiology, and End Results Program at the National Cancer Institute
Trends in inflammatory breast carcinoma incidence and survival: The Surveillance, Epidemiology, and End Results Program at the National Cancer Institute
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DOI：
10.1093/jnci/dji172
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发表时间：
2005-07-06
影响因子：
10.3
通讯作者：
Levine, PH
中科院分区：
文献类型：
--
作者：
Hance, KW;Anderson, WF;Levine, PH
背景：炎症性乳腺癌（IBC）似乎是一种不同于局部晚期乳腺癌（LABC）的临床病理学实体。我们检查了IBC在监视，流行病学和最终结果（SEER）的发病率和生存趋势。具有案例定义的编程数据，旨在捕获其许多独特的临床和病理特征。方法：我们分析了1988年至2000年之间的SEER 9登记处诊断出的乳腺癌病例（n = 180 224）。使用SEER的“疾病范围”代码与国际疾病的肿瘤学疾病分类8530对乳腺癌病例进行了分类。 /3并分类为IBC（n = 3648），LABC（n = 3636）和非T4乳腺癌（n = 172 940）。我们比较了使用SEER*STAT的乳腺癌亚型和种族的3年间隔内的发病率变化。使用Kaplan-Meier曲线和对数级统计来评估乳腺癌亚型和种族的生存差异。所有统计检验均两侧。结果：在1988年至1990年，1997年和1999年之间，IBC发病率（每100000名女性）从2.0增加到2.5（p
Background: Inflammatory breast carcinoma (IBC) appears to be a clinicopathologic entity distinct from noninflammatory locally advanced breast cancer (LABC). We examined incidence and, survival trends for IBC in Surveillance, Epidemiology, and End Results (SEER).Program data with a case definition designed to capture many of its unique clinical and pathologic characteristics. Methods: We analyzed breast cancer cases diagnosed in the SEER 9 Registries (n = 180 224), between 1988 and 2000. Breast cancer cases were categorized using SEER's "Extent of Disease" codes in combination with International Classification of Diseases for Oncology morphology code 8530/3 and classified as IBC (n = 3648), LABC (n = 3636), and non-T4 breast cancer (n = 172 940). We compared changes in incidence rates over 3-year intervals by breast cancer subtype and race using SEER*Stat. Survival differences by breast cancer subtype and race were assessed using Kaplan-Meier curves and log-rank statistics. All statistical tests were two-sided. Results: Between 1988 and 1990 and 1997 and 1999, IBC incidence rates (per 100000 womanyears) increased from 2.0 to 2.5 (P