Intrinsic projections within visual cortex: evidence for orientation-specific local connections.
Intrinsic projections within visual cortex: evidence for orientation-specific local connections.
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视觉皮层内的内在投射：特定方向局部连接的证据。
DOI：
10.1073/pnas.82.3.935
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发表时间：
1985
影响因子：
11.1
通讯作者：
Stryker,MP
中科院分区：
文献类型：
--
作者：
Matsubara,J;Cynader,M;Swindale,NV;Stryker,MP
采用电生理和解剖学相结合的方法，研究了猫视皮层18区内神经元内连接的功能组织。生理记录首先被用来映射的方向偏好，眼优势，和相对于皮层表面的感受野位置的分布。接下来，将凝集素缀合的辣根过氧化物酶局部注射到区域18内的生理学鉴定区域中。我们发现：（i）局部皮层互连优先在具有正交优选取向的细胞群之间进行，并且独立于皮层细胞的眼优势，（ii）皮层中视觉空间的地图是各向异性的，垂直视觉空间的放大因子至少是水平视觉空间的两倍，以及（iii）皮质投射的图案补偿了功能不对称性，使得互连的细胞群表示视觉空间的大致圆形区域。
The functional organization of intrinsic connections within area 18 of cat visual cortex was studied using combined electrophysiological and anatomical techniques. Physiological recordings were first used to map the distribution of orientation preference, ocular dominance, and receptive-field location relative to the cortical surface. Next, localized injections of lectin-conjugated horseradish peroxidase were made into physiologically identified regions within area 18. We found that (i) the local cortical interconnections are made preferentially between cell populations with orthogonal preferred orientations and are independent of the ocular dominance of the cortical cells, (ii) the map of visual space in the cortex is anisotropic with the magnification factor for vertical at least twice that for horizontal visual space, and (iii) the pattern of cortical projections compensates for the functional asymmetry so that a population of interconnected cells represents a roughly circular region of visual space.