Computed Tomographic Blend Sign Is Associated With Computed Tomographic Angiography Spot Sign and Predicts Secondary Neurological Deterioration After Intracerebral Hemorrhage
Computed Tomographic Blend Sign Is Associated With Computed Tomographic Angiography Spot Sign and Predicts Secondary Neurological Deterioration After Intracerebral Hemorrhage
复制标题
DOI：
10.1161/strokeaha.116.014068
复制
发表时间：
2017-01-01
期刊：
影响因子：
8.3
通讯作者：
Hanning, Uta
中科院分区：
文献类型：
--
作者：
Sporns, Peter B.;Schwake, Michael;Hanning, Uta
脑出血患者的背景和目的的早期血肿生长是功能不良结果的独立预测指标。最近，新型混合符号（BS）被引入是一种新成像标志，用于预测非对比度计算机断层扫描中血肿的生长。预测血肿大小增加的另一个参数是在计算机断层扫描中可见的良好的点标志（SS）。因此，我们旨在阐明已建立的SS和新型BS及其预测次级神经系统劣化的价值之间的关联。（1）在非冲突术中的自发性脑出血和（2）无关计算机摄影和计算机构图表演的范围内的无关计算机上的自发性脑出血标准（1）脑内出血的确认。我们定义了二元结果（二级神经系统恶化与无次级恶化）。作为继发神经系统恶化，我们在标准标准下定义了（1）（1）早期半晶状切除术或（2）在症状发作后的前48小时内，格拉斯哥昏迷量表的次级减少。182例自发性内部出血，37（37（20.3％））和39％的人（b.21）（21）（b）和39.29岁（21）（21）（21）（21）在81例继发性恶化的患者中，有31例（38.3％）患有BS和SS。多变量逻辑回归分析鉴定出血肿的体积（几率比，每毫升1.07; p
Background and Purpose-Significant early hematoma growth in patients with intracerebral hemorrhage is an independent predictor of poor functional outcome. Recently, the novel blend sign (BS) has been introduced as a new imaging sign for predicting hematoma growth in noncontrast computed tomography. Another parameter predicting increasing hematoma size is the well-established spot sign (SS) visible in computed tomographic angiography. We, therefore, aimed to clarify the association between established SS and novel BS and their values predicting a secondary neurological deterioration.Methods-Retrospective study inclusion criteria were (1) spontaneous intracerebral hemorrhage confirmed on noncontrast computed tomography and (2) noncontrast computed tomography and computed tomographic angiography performed on admission within 6 hours after onset of symptoms. We defined a binary outcome (secondary neurological deterioration versus no secondary deterioration). As secondary neurological deterioration, we defined (1) early hemicraniectomy under standardized criteria or (2) secondary decrease of Glasgow Coma Scale of >3 points, both within the first 48 hours after symptom onset.Results-Of 182 patients with spontaneous intracerebral hemorrhage, 37 (20.3%) presented with BS and 39 (21.4%) with SS. Of the 81 patients with secondary deterioration, 31 (38.3%) had BS and SS on admission. Multivariable logistic regression analysis identified hematoma volume (odds ratio, 1.07 per mL; P