Diffusion Magnetic Resonance Imaging: What Water Tells Us about Biological Tissues
Diffusion Magnetic Resonance Imaging: What Water Tells Us about Biological Tissues
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DOI：
10.1371/journal.pbio.1002246
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发表时间：
2015-07-01
期刊：
影响因子：
9.8
通讯作者：
Iima, Mami
中科院分区：
文献类型：
--
作者：
Le Bihan, Denis;Iima, Mami
扩散磁共振成像(MRI)自20世纪80年代中期问世以来，通过测量水分子在组织中的随机运动，揭示其微结构，已成为现代神经成像的支柱。它的主要临床领域一直是急性脑中风和神经疾病的诊断，但它也用于体内癌症病变的检测和处理。它还可以产生大脑中令人惊叹的白质轨迹图，有可能帮助理解一些精神障碍。然而，为了充分发挥这种方法的潜力，需要对控制组织中水扩散的机制有更深入的了解。
Since its introduction in the mid-1980s, diffusion magnetic resonance imaging (MRI), which measures the random motion of water molecules in tissues, revealing their microarchitecture, has become a pillar of modern neuroimaging. Its main clinical domain has been the diagnosis of acute brain stroke and neurogical disorders, but it is also used in the body for the detection and management of cancer lesions. It can also produce stunning maps of white matter tracks in the brain, with the potential to aid in the understanding of some psychiatric disorders. However, in order to exploit fully the potential of this method, a deeper understanding of the mechanisms that govern the diffusion of water in tissues is needed.