Sensory processing during kinesthetic aftereffect following illusory hand movement elicited by tendon vibration
Sensory processing during kinesthetic aftereffect following illusory hand movement elicited by tendon vibration
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DOI：
10.1016/j.brainres.2006.07.062
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发表时间：
2006-10-09
期刊：
影响因子：
2.9
通讯作者：
Naito, Eiichi
中科院分区：
文献类型：
--
作者：
Kito, Tomonori;Hashimoto, Toshihiro;Naito, Eiichi
我们研究了人类感觉运动系统如何引发体感后遗症。肢体的肌腱振动会激发肌梭传入神经，从而引发肢体的错觉运动。振动停止后，即使没有振动募集的传入输入，也经常会经历短暂的感觉，即振动的肢体返回其原始位置（动觉后效应）。我们振动右腕伸肌或屈肌的肌腱，引起虚幻的屈曲或伸展运动，随后产生相应的伸展或屈曲后效应。首先，我们从心理物理学角度研究了先前的幻觉运动如何影响后效。其次，我们检查了后遗症期间的皮质脊髓兴奋性，以评估其自幻觉期间的变化。我们测量了单脉冲经颅磁刺激对侧运动皮层（M1）的手部诱发的运动诱发电位的幅度。所有19名受试者都经历了后遗症，后遗症的量大约是之前幻觉的70%。幻觉过程中，非振动肌肉的皮质脊髓兴奋性比振动肌肉的皮质脊髓兴奋性增加更多，从而反映了幻觉的方向。在后效过程中，只有非振动肌肉的兴奋性显着降低，振动肌肉没有变化，这反过来又导致两块肌肉之间兴奋性不平衡的模式相反，兴奋性不平衡的程度与 后遗症的感觉。动觉后效似乎是由先前的幻觉运动决定的感觉过程引起的。来自受刺激和未受刺激肌肉的不平衡感觉信息的运动皮质处理可能有助于引起动觉后效应。 (c) 2006 Elsevier B.V. 保留所有权利。
We investigated how the human sensory-motor system elicits a somatosensory aftereffect. Tendon vibration of a limb excites the muscle spindle afferents that contribute to eliciting illusory movements of the limb. After the cessation of vibration, a transient sensation in which the vibrated limb returns towards its original position (kinesthetic aftereffect) is often experienced, even in the absence of the afferent inputs recruited by the vibration. We vibrated the tendon of either the right wrist extensor or flexor muscle that elicited an illusory flexion or extension movement, which was followed by its corresponding extension or flexion aftereffect. First, we psychophysically investigated how the preceding illusory movement affects the aftereffect. Second, we examined the cortico-spinal excitability during the aftereffect to evaluate its changes from the time during the illusion. We measured the amplitude of the motor-evoked potential that is evoked by a single-pulse transcranial magnetic stimulation to the hand section of the contralateral motor cortex (M1). All 19 subjects experienced the aftereffect, and the amount of aftereffect was approximately 70% of the preceding illusion. During the illusion, the cortico-spinal excitability increased more in non-vibrated than in vibrated muscle, so as to reflect the illusory directions During the aftereffect, the excitability was significantly reduced only in the non-vibrated muscle, with no change in the vibrated muscle, which, in turn, caused an opposite pattern in the unbalanced excitability between the two muscles, and the degree of unbalanced excitability was correlated with the sensation of aftereffect. The kinesthetic aftereffect seems to be elicited by a sensory process that is determined by the preceding illusory movements. Motor-cortical processing of the unbalanced sensory information from the stimulated and non-stimulated muscles may contribute to the elicitation of kinesthetic aftereffect. (c) 2006 Elsevier B.V. All rights reserved.