Modified STOP-bang questionnaire incorporating morning dry mouth and BMI adjustment in China: a retrospective study of 590 patients
Modified STOP-bang questionnaire incorporating morning dry mouth and BMI adjustment in China: a retrospective study of 590 patients
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DOI：
10.1080/17476348.2023.2292136
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发表时间：
2023-11-02
影响因子：
3.9
通讯作者：
Wang，Guangfa
中科院分区：
文献类型：
--
作者：
Ma，Xiaoyu;Zhang，Cheng;Wang，Guangfa
背景晨起口干（Morning dry mouth，MDM）是阻塞性睡眠呼吸暂停（Obstructive Sleep Apnea，OSA）的常见症状，但目前的OSA筛查工具忽略了这一点。目的通过增加MDM症状，提高Stop-Bang问卷（SBQ）的特异性。他们接受了多导睡眠图检查。本研究将MDM症状纳入SBQ，并将体重指数（BMI）阈值调整为28 kg/m2。结果83.1%的患者被诊断为OSA，61.4%的患者报告为MDM。多元回归分析证实，MDM对呼吸暂停低通气指数（AHI）有显著影响。用MDM调整SBQ显示灵敏度略有下降，但特异性提高，特别是当使用> 28 kg/m2的BMI阈值时。AHI ≥ 5次/h和AHI ≥ 15次/h时，以BMI >28 kg/m2的MDM患者调整SBQ获得的Youden指数最高。结论将MDM症状纳入SBQ，调整BMI阈值，可提高OSA诊断的特异性。
BackgroundMorning dry mouth (MDM) is a common symptom of Obstructive Sleep Apnea (OSA) yet current OSA screening tools overlook it.ObjectiveTo enhance the specificity of the Stop-Bang questionnaire (SBQ) by adding an MDM symptom.MethodA retrospective analysis on 590 patients from Peking University First Hospital (2013–2018) suspected of OSA was conducted. They underwent polysomnography. The research incorporated the MDM symptom into SBQ and adjusted the body mass index (BMI) threshold to 28 kg/m2. Predictive parameters were then calculated.Results83.1% patients were diagnosed with OSA, with 61.4% reporting MDM. Multivariate regression confirmed MDM significantly influenced Apnea-Hypopnea Index (AHI). Adjusted SBQ with MDM showed a slight decrease in sensitivity but improved specificity, especially when using a BMI threshold of > 28 kg/m2. For AHI ≥ 5 events/h and AHI ≥ 15 events/h, adjusted SBQ with MDM (BMI >28 kg/m2) obtained the highest Youden index.ConclusionIncorporating the MDM symptom into SBQ and adjusting the BMI threshold enhances the diagnostic specificity for OSA.