THE RELATION BETWEEN LIGHT-INDUCED DISCHARGE IN THE SUPRACHIASMATIC NUCLEUS AND PHASE-SHIFTS OF HAMSTER CIRCADIAN-RHYTHMS

THE RELATION BETWEEN LIGHT-INDUCED DISCHARGE IN THE SUPRACHIASMATIC NUCLEUS AND PHASE-SHIFTS OF HAMSTER CIRCADIAN-RHYTHMS
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DOI:
10.1016/0006-8993(92)90191-b
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发表时间:
1992-12-11
期刊:
影响因子:
2.9
通讯作者:
GANSHIRT, G
GANSHIRT, G
中科院分区:
医学3区
文献类型:
--
作者:
MEIJER, JH;RUSAK, B;GANSHIRT, G

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通过行为学和电生理学的结合研究,探讨了仓鼠视交叉上核(SCN)细胞的神经生理激活在昼夜节律起搏器相移中的作用。一项电生理研究检查了光呈现模式与SCN诱导放电率之间的关系。行为实验检验了光呈现模式和相移幅度之间的关系。这些结果的结合提供了SCN中诱导神经放电与昼夜活动节律相移之间关系的间接分析。数据表明,相移的大小与光诱导的放电速率变化呈单调关系,而不是线性关系。
The role of neurophysiological activation of suprachiasmatic nucleus (SCN) cells in phase shifting the circadian pacemaker of the hamster was investigated in a combined behavioural and electrophysiological study. An electrophysiological study examined the relation between the pattern of light presentation and the induced discharge rate in the SCN. Behavioural experiments examined the relation between the pattern of light presentation and the magnitude of phase shift induced. The combination of these results provides an indirect assay of the relations between induced neural discharge in the SCN and phase shifts of the circadian activity rhythm. The data indicate that the magnitude of phase shifts is monotonically, but not linearly, related to photically induced changes in discharge rate.