TUMORS IN RUBINSTEIN-TAYBI SYNDROME
TUMORS IN RUBINSTEIN-TAYBI SYNDROME
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DOI：
10.1002/ajmg.1320560125
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发表时间：
1995-03-13
期刊：
影响因子：
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通讯作者：
RUBINSTEIN, JH
中科院分区：
文献类型：
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作者：
MILLER, RW;RUBINSTEIN, JH
自1989年以来，Rubinstein-Taybi综合征中报告的14个肿瘤，加上以前报告的22个，开始显示出神经和发育肿瘤的模式，特别是头部，这是畸形的综合征。神经系统肿瘤12例：少突胶质细胞瘤、髓母细胞瘤、神经母细胞瘤、良性脑膜瘤各2例，嗜铬细胞瘤1例，其他良性肿瘤3例;鼻咽横纹肌肉瘤2例;平滑肌肉瘤、神经母细胞瘤、胚胎癌各1例。在其他良性肿瘤中，有一个牙瘤，一个脉络膜瘤，一个皮样囊肿和两个毛母质瘤。(C)1995 Wiley-Liss，Inc.
The 14 tumors reported in Rubinstein-Taybi syndrome since 1989, when added to the 22 previously reported, are beginning to show a pattern of neural and developmental tumors, especially of the head, which is malformed in the syndrome. Among the neoplasms were 12 of the nervous systems: 2 each of oligodendroglioma, medulloblastoma, neuroblastoma, and benign meningioma, a pheochromocytoma, and 3 other benign tumors; 2 of nasopharyngeal rhabdomyosarcoma; and 1 each of leiomyosarcoma, seminoma, and embryonal carcinoma. Among the other benign tumors were an odontoma, a choristoma, a dermoid cyst, and 2 pilomatrixomas. (C) 1995 Wiley-Liss, Inc.