Versatile synthesis of fluorescent, cross-linked peptides as biological probes with the advantage of high helix content
Versatile synthesis of fluorescent, cross-linked peptides as biological probes with the advantage of high helix content
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作为生物探针的荧光交联肽的多功能合成，具有高螺旋含量的优势
DOI：
10.1007/s11164-012-0651-5
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发表时间：
2013
影响因子：
3.3
通讯作者：
Kazuhisa Fujimoto
中科院分区：
文献类型：
--
作者：
Kazutaka Hirakawa;Shiori Inoue;Kazuhisa Fujimoto
在短肽的 N 末端引入多种荧光团，用作生物探针。荧光肽与鸟氨酸 (Orn) 残基的氨基酸侧链之间的二乙炔交联剂交联，产生具有高螺旋含量的肽。
A variety of fluorophores were introduced at the N-termini of short peptides for use as biological-probes. The fluorescent peptides were cross-linked with a diacetylenic cross-linking agent between the amino acid side chains of ornithine (Orn) residues to produce peptides with high helix content.