Antibacterial and Antifungal Activities of Nine Medicinal Plants from Zaire

Antibacterial and Antifungal Activities of Nine Medicinal Plants from Zaire
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扎伊尔九种药用植物的抗菌和抗真菌活性

DOI:
10.3109/13880209409083012
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发表时间:
1994
期刊:
影响因子:
--
通讯作者:
L. Williams
L. Williams
中科院分区:
--
文献类型:
--
作者:
D. Muanza;B. W. Kim;K. Euler;L. Williams

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摘要对再热药用植物进行了提取和体外抗菌、抗真菌活性筛选。在所研究的9种植物中,有6种植物的提取物对肺炎克雷伯氏菌、金黄色葡萄球菌和变形链球菌有显著的抑菌活性,4种植物的提取物对黑曲霉、白色念珠菌和石膏小孢子菌有显著的抑菌活性。粗制甲醇提取物的MIC值为62.5MICg/ml,活性成分主要分布在其乙酸乙酯和水提物中,其抑菌和杀菌活性成分主要分布在其乙酸乙酯和水提物中。这些结果可能为分离具有生物意义的化合物提供依据。
AbstractZairean medicinal plants were extracted and screened for in vitro antibacterial and antifungal activities. Of nine plants investigated, extracts of six plants (Alchornea cordifolia, Bridelia ferruginea, Eucalyptus citriodora, Hymenocardia acida, Maprounea africana and Sida rhombifolia) demonstrated a marked antibacterial activity against the microorganisms Klebsiella pneumoniae, Staphylococcus aureus and Streptococcus mutans; and extracts of four plants (A. cordifolia, E. citriodora, M. africana and S. rhombifolia) exhibited significant antifungal activity against Aspergillus niger, Candida albicans and Microsporum gypseum. Extracts from A. cordifolia and M. africana were the most active with a MIC value of 62.5 μg/ml. Fractionation of the crude methanol extracts revealed that the bactericidal and fungicidal constituents of the active plants were mainly distributed in their ethyl acetate and aqueous fractions. These results may provide a basis for the isolation of compounds of biological interest ...
北村,R.;新地,M.:(1986)
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