Serum 25(OH)D Level on Hospital Admission Associated With COVID-19 Stage and Mortality
Serum 25(OH)D Level on Hospital Admission Associated With COVID-19 Stage and Mortality
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DOI：
10.1093/ajcp/aqaa252
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发表时间：
2021-03-01
影响因子：
3.5
通讯作者：
Martens, Geert A.
中科院分区：
文献类型：
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作者：
De Smet, Dieter;De Smet, Kristof;Martens, Geert A.
目的：维生素D缺乏症先前与2019冠状病毒病（COVID-19）的发病率和严重程度相关。我们调查了入院时血清25-羟基维生素D（25（OH）D）水平与COVID-19肺炎的放射学分期和结局之间的关系。对186例严重急性呼吸综合征冠状病毒2型进行了回顾性观察试验2020年3月1日至2020年4月7日期间住院的SARS-CoV-2感染者，入院时进行胸部计算机断层扫描（CT）和25（OH）D测量。采用多元回归分析研究维生素D缺乏（25（OH）D
Objectives: Vitamin D deficiency was previously correlated with incidence and severity of coronavirus disease 2019 (COVID-19). We investigated the association between serum 25-hydroxyvitamin D (25(OH)D) level on admission and radiologic stage and outcome of COVID-19 pneumonia.Methods: A retrospective observational trial was done on 186 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals hospitalized from March 1, 2020, to April 7, 2020, with combined chest computed tomography (CT) and 25(OH)D measurement on admission. Multivariate regression analysis was performed to study if vitamin D deficiency (25(OH)D