VH1, a provascular cell-specific receptor kinase that influences leaf cell patterns in Arabidopsis
VH1, a provascular cell-specific receptor kinase that influences leaf cell patterns in Arabidopsis
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DOI：
10.1105/tpc.005884
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发表时间：
2002-11-01
期刊：
影响因子：
11.6
通讯作者：
Nelson, T
中科院分区：
文献类型：
--
作者：
Clay, NK;Nelson, T
叶片叶脉模式的形成非常适合用于研究识别并响应时空信息的信号通路，因为该模式是二维的且可遗传，并且所形成的叶脉会影响周围正在分化的叶细胞类型的三维空间组织。我们鉴定出一个维管束原/原形成层细胞特异性基因，它编码一种富含亮氨酸重复序列的受体激酶，我们将其命名为“维管高速公路1”（VH1）。VH1表达区域和水平的变化标志着在早期维管发育过程中从非定向的维管束原状态向定向的原形成层状态的转变。其编码序列、表达模式以及转基因表型共同表明，VH1将细胞外的时空信号转导至维管束原/原形成层细胞中的下游细胞分化反应。
The formation of the venation pattern in leaves is ideal for examining signaling pathways that recognize and respond to spatial and temporal information, because the pattern is two-dimensional and heritable and the resulting veins influence the three-dimensional spatial organization of the surrounding differentiating leaf cell types. We identified a provascular/procambial cell-specific gene that encodes a Leu-rich repeat receptor kinase, which we named VASCULAR HIGHWAY1 (VH1). A change in the expression domain and level of VH1 marks the transition from an uncommitted provascular state to a committed procambial state in early vascular development. The coding sequence, expression pattern, and transgenic phenotypes together suggest that VH1 transduces extracellular spatial and temporal signals into downstream cell differentiation responses in provascular/procambial cells.