Three-year prognosis of depression in the community-dwelling elderly
Three-year prognosis of depression in the community-dwelling elderly
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DOI：
10.1192/bjp.176.5.453
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发表时间：
2000-05-01
影响因子：
10.5
通讯作者：
Lawlor, BA
中科院分区：
文献类型：
--
作者：
Denihan, A;Kirby, M;Lawlor, BA
抑郁症是社区老年人最常见的精神障碍，目的探讨社区老年人抑郁症的3年预后及影响因素。一些因素进行了调查，与恢复，或持久性，depression.Results随访时，30.2%的抑郁症患者已经死亡，34.9%的持续或复发的情况下，抑郁症，24.5%的其他情况下，或subcase水平的精神疾病和10.4%已完全恢复。身体不健康。丧亲之痛和积极的抑郁症家族史与不良结局相关，而抗抑郁药物治疗显着改善预后。结论在社区居住的受试者晚年抑郁症是一种慢性疾病。然而.对抗抑郁药物的积极反应表明应该积极治疗。利益声明这项研究部分由爱尔兰健康研究委员会资助。
Background Depression is the most common mental disorder in the community-dwelling elderly.Aims To determine the three-year prognosis of depression in a cohort of 127 community-dwelling elderly subjects and identify factors relevant to outcome.Method The subjects, diagnosed depressed at year 0 using the GMS-AGECAT package, were followed up three years later. A number of factors were investigated for an association with recovery from, or persistence of, depression.Results At follow-up, 30.2% of the depressed subjects had died, 34.9% had persistent or relapsed case-level depression, 24.5% had other case- or subcase-level mental illness and 10.4% had recovered completely. Physical ill-health. bereavement and positive family history of depression were associated with poor outcome, whereas treatment with antidepressant medication significantly improved prognosis.Conclusions Late-life depression in community-dwelling subjects is a chronic condition. However. the positive response to antidepressant medication suggests that it should be vigorously treated.Declaration of interest This study was partly funded by the Health Research Board of Ireland.