Coordination-Driven Stereospecific Control Strategy for Pure Cycloisomers in Solid-State Diene Photocycloaddition
Coordination-Driven Stereospecific Control Strategy for Pure Cycloisomers in Solid-State Diene Photocycloaddition
复制标题
固态二烯光环加成中纯环异构体的配位驱动立体定向控制策略
DOI：
10.1021/jacs.9b12358
复制
发表时间：
2020
影响因子：
15
通讯作者：
Jian-Ping Lang
中科院分区：
文献类型：
--
作者：
Meng-Fan Wang;Yan Mi;Fei-Long Hu;Zheng Niu;Xian-Hong Yin;Qin Huang;Hui-Fang Wang;Jian-Ping Lang
得到纯的产物而不产生异构体副产物是许多化学家追求的目标。光化学反应是一种非常重要的合成方法，简单直接，但选择性低。本文提出了一种基于配位相互作用的定向合成策略，实现了异构环状化合物在光环加成反应中的精确立体化学控制。通过配位作用固定反应物，可以调节反应物的排列和构型，从而首次成功地制备了所有相关的光环加成产物，没有异构体副产物。本工作不仅为合成纯环状化合物提供了一条新的途径，而且拓展了光环加成反应的应用范围。
To obtain a pure product without the isomer byproducts is a goal that many chemists are pursuing. As one kind of very important synthesis method, the photochemical reaction is simple and straightforward yet low-selective. In this work, a coordination interactionbased oriented synthesis strategy has been proposed to realize the precise stereochemical control of the isomeric cyclic compounds in the photocycloaddition reaction. Through fixing the reactants via coordination interactions, the arrangements and configurations of the reactants can be adjusted, thereby successfully producing all of the related photocycloaddition products without isomer byproducts for the first time. This work not only provides a new route to synthesize the pure cyclic compounds but also expands the application of the photocycloaddition reaction.