Full Moon and Out-of-Hospital Cardiac Arrest in Japan - Population-Based, Double-Controlled Case Series Analysis.
Full Moon and Out-of-Hospital Cardiac Arrest in Japan - Population-Based, Double-Controlled Case Series Analysis.
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DOI：
10.1253/circrep.cr-18-0030
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发表时间：
2019-05-08
期刊：
影响因子：
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通讯作者：
Kitamura T
中科院分区：
文献类型：
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作者：
Sado J;Morikawa K;Hattori S;Kiyohara K;Matsuyama T;Izawa J;Iwami T;Kitamura Y;Sobue T;Kitamura T
背景资料：人们普遍认为，满月会影响人类的行为或各种疾病的发生和结果;因此，在满月之夜，院外心脏骤停（OHCA）的发生率可能会增加。方法 和 结果：这项全国性的、基于人群的观察性研究连续招募了2005年至2016年期间在日本尝试复苏的OHCA患者。主要结果指标是OHCA的发生率。基于双控制方法，假设泊松抽样，我们评估了在满月之夜发生的OHCA事件的平均数量与在控制之夜发生的OHCA事件的平均数量相比，控制之夜包括在满月之夜之前和之后1周的相同日历日发生的事件。共有29，552个OHCA发生在148个满月之夜，58，707个OHCA发生在296个对照之夜，符合分析条件。OHCA的发生率在满月和对照组之间没有差异（每晚199.7 vs. 198.3;相对危险度[RR]，1.007; 95%CI：0.993-1.021）。在亚组分析中，与对照夜晚相比，心源性和非心源性OHCA发生的RR分别为1.013（95%CI：0.994-1.032，P=0.166）和0.998（95%CI：0.977-1.020，P=0.866）。结论：在这一人群中，满月和对照夜间OHCA的发生率没有显著差异。
Background: It is commonly believed that a full moon affects human behavior or the occurrence and outcome of various diseases; thus, the occurrence of out-of-hospital cardiac arrest (OHCA) might increase during full moon nights. Methods and Results: This nationwide, population-based observational study consecutively enrolled OHCA patients in Japan with attempted resuscitation between 2005 and 2016. The primary outcome measure was the occurrence of OHCA. Based on the double-control method, assuming Poisson sampling, we evaluated the average number of OHCA events that occurred on full moon nights compared with that which occurred on control nights, which included events that occurred on the same calendar days 1 week before and after the full moon nights. A total of 29,552 OHCA that occurred on 148 full moon nights and 58,707 OHCA that occurred on 296 control nights were eligible for analysis. The occurrence of OHCA did not differ between full moon and control nights (199.7 vs. 198.3 per night; relative risk [RR], 1.007; 95% CI: 0.993–1.021). On subgroup analysis, compared with control nights, the RR of OHCA occurrence were 1.013 (95% CI: 0.994–1.032, P=0.166) and 0.998 (95% CI: 0.977–1.020, P=0.866) for cardiac and non-cardiac origins, respectively. Conclusions: In this population, there was no significant difference in OHCA occurrence between full moon and control nights.