Australia's national Q fever vaccination program
Australia's national Q fever vaccination program
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DOI：
10.1016/j.vaccine.2009.02.007
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发表时间：
2009-03-23
期刊：
影响因子：
5.5
通讯作者：
McIntyre, Peter B.
中科院分区：
文献类型：
--
作者：
Gidding, Heather F.;Wallace, Cate;McIntyre, Peter B.
2002年，澳大利亚推出了一项由国家资助的Q热疫苗接种计划。对这一独特项目的评估包括项目实施前和实施后Q热的接收、安全性、通知率和住院率。计划的接受程度从屠宰场工人的接近100%到农民的43%不等。最常见的不良反应是注射部位反应。在2002年至2006年期间，Q热病报告率下降了50%以上，特别是在年轻成年男性中，这与屠宰场劳动力的情况一致。住院数据也显示了类似的趋势。现有证据表明，澳大利亚的Q热疫苗接种计划产生了重大影响：这样的计划值得其他具有类似Q热疾病负担的国家考虑。2009爱思唯尔有限公司版权所有。
A nationally funded Q fever vaccination program was introduced in Australia in 2002. The evaluation of this unique program included measures of program uptake, safety, and notification and hospitalisation rates for Q fever pre- and post-program implementation. Program uptake ranged from close to 100% amongst abattoir workers to 43% in farmers. The most commonly reported adverse event was injection site reaction. Q fever notification rates declined by over 50% between 2002 and 2006, particularly in young adult males, consistent with the profile of the abattoir workforce. Hospitalisation data showed similar trends. Available evidence suggests a significant impact of Australia's Q fever vaccination program: such a program merits consideration in other countries with a comparable Q fever disease burden. (C) 2009 Elsevier Ltd. All rights reserved.