THE HAGFISH SLIME GLAND - A MODEL SYSTEM FOR STUDYING THE BIOLOGY OF MUCUS

THE HAGFISH SLIME GLAND - A MODEL SYSTEM FOR STUDYING THE BIOLOGY OF MUCUS
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DOI:
10.1126/science.7302586
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发表时间:
1981-01-01
期刊:
影响因子:
56.9
通讯作者:
KOCH, EA
KOCH, EA
中科院分区:
综合性期刊1区
文献类型:
--
作者:
DOWNING, SW;SALO, WL;KOCH, EA

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八目盲鳗[Eptatretus stelvis]粘液腺可以提供一个模型系统,用于研究粘液生物学的某些方面。通过电刺激麻醉的八目鳗获得非水合形式的粘液,并将分泌物搅拌成硫酸铵。然后使用离心和过滤来分离2种主要分泌产物,粘液囊泡和丝。该模型的具体优势和潜在的应用研究进行了讨论。
The hagfish [Eptatretus stouti] slime gland may provide a model system for studying certain aspects of the biology of mucus. Mucus is obtained in nonhydrated form by electrically stimulating the anesthetized hagfish and the secretions are stirred into ammonium sulfate. Centrifugation and filtration are then used to isolate the 2 major secretory products, mucous vesicles and threads. Specific advantages of the model and potential applications for research are discussed.