Self-assembly of sugar-based amphiphile on carbon nanotubes for protein adsorption
Self-assembly of sugar-based amphiphile on carbon nanotubes for protein adsorption
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碳纳米管上糖基两亲物的自组装用于蛋白质吸附
DOI：
10.1016/j.ces.2011.06.048
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发表时间：
2011-10
影响因子：
4.7
通讯作者：
Zhigang Zheng
中科院分区：
文献类型：
--
作者：
Wei Feng;Rongmei Luo;JingXiao Jing;Peijun Ji;Zhigang Zheng
多壁碳纳米管(MWNTs)的非共价功能化是一种新的方法，它允许碳水化合物通过疏水相互作用呈现在其表面。该方法是基于糖基两亲分子在醇/水混合溶剂中在多壁碳纳米管上的自组装，通过紫外(UV)、拉曼光谱、傅立叶变换红外光谱(FTIR)、X射线光电子能谱(XPS)、X射线衍射(XRD)和高分辨电子显微镜(HRTEM)对其进行了研究。研究表明，醇不仅可以促进两亲分子在多壁碳纳米管上的自组装，而且可以调节组装后的两亲分子的数量和构象。研究了功能化多壁碳纳米管对牛血清白蛋白(BSA)的吸附，并用圆二色谱(CD)对其进行了表征。结果表明，吸附的牛血清白蛋白的构象得到了很好的保存。研究表明，外表面带有二糖基团的功能化多壁碳纳米管在水中具有良好的分散性和生物相容性，可能在分子识别方面具有潜在的应用前景。
A new approach has been developed for the non-covalent functionalization of multiwalled carbon nanotubes (MWNTs), which allows a presentation of carbohydrate on their surface by hydrophobic interactions. The approach is based on the self-assembly of a sugar-based amphiphile on MWNTs in alcohol/water mixtures, which has been investigated by means of ultraviolet (UV), Raman spectra, Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and high-resolution transmission electron microscopy (HRTEM). It has been demonstrated that alcohols not only can promote the self-assembly of the amphiphile on MWNTs but also can regulate the amount and conformation of the assembled amphiphile. The adsorption of bovine serum albumin (BSA) onto functionalized MWNTs has been studied and characterized with circular dichroism (CD) spectra. The results showed that the conformation of adsorbed BSA has been well preserved. It has been demonstrated that, the functionalized MWNTs with disaccharide groups on their exterior surface have a good dispersibility in water and are biocompatible, may have a potential application of molecular recognition.
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影响因子：
1.7
作者：
Kristina L. Parry;A. Shard;R. Short;R. White;J. Whittle;A. Wright
通讯作者：
Kristina L. Parry;A. Shard;R. Short;R. White;J. Whittle;A. Wright
DOI：
10.1002/chin.200339252
发表时间：
2003-07
期刊：
ChemInform
影响因子：
--
作者：
Tong Lin;V. Bajpai;T. Ji;L. Dai
通讯作者：
Tong Lin;V. Bajpai;T. Ji;L. Dai
影响因子：
6.2
作者：
Kubo, S;Kadla, JF
通讯作者：
Kadla, JF
影响因子：
16.6
作者：
Wu, Peng;Chen, Xing;Bertozzi, Carolyn R.
通讯作者：
Bertozzi, Carolyn R.
影响因子：
4.4
作者：
Chennamsetty, N;Bock, H;Gubbins, KE
通讯作者：
Gubbins, KE