Relationship between Hematoma Volume and Motor Impairment in Putaminal Hemorrhage
Relationship between Hematoma Volume and Motor Impairment in Putaminal Hemorrhage
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壳核出血血肿量与运动障碍的关系
DOI：
10.1016/j.jstrokecerebrovasdis.2020.104812
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发表时间：
2020
影响因子：
2.5
通讯作者：
Sonoda Shigeru
中科院分区：
文献类型：
--
作者：
Ohnishi Hitoshi;Takeda Kotaro;Watanabe Makoto;Maeshima Shinichiro;Sonoda Shigeru
目的：计算机断层扫描(CT)用于对疑似中风患者的初步评估。使用初始CT图像预测运动结果对于临床康复非常重要。然而，少数文献报道的关于壳核出血患者的血肿量和运动结果的结果并不一致。为明确壳核出血患者的血肿方向及血肿体积与运动功能的关系，我们对170例壳核出血后亚急性期患者进行了卒中时CT血肿方向的评估。对每一组，计算Spearman相关系数以研究血肿体积与运动结果之间的关系。采用卒中损伤评估集的运动项目评价患者的运动功能。结果：单纯血肿扩散至内囊后肢的血肿量与所有运动项目均显著相关(Bonferroni校正P<；0.05)。另一方面，在几乎所有其他组中，血肿量和运动结果之间并不存在显著的相关性。结论：壳核出血后的运动结果可以通过卒中时CT图像评估血肿向皮质脊髓束及其体积的进展来预测。
Purpose:Computed tomography (CT) is used for initial assessment of patients with suspected stroke. Motor outcome prediction using the initial CT image is important for clinical rehabilitation. However, there is inconsistency in the results reported by the few publications on hematoma volume and motor outcomes in patients with putaminal hemorrhage. To clarify the direction of hematoma and relationship between the hematoma volume and motor outcomes in patients with putaminal hemorrhage using an initial CT image, we evaluated the volume of direction of hematoma in 170 patients in the subacute phase after putaminal hemorrhage using CT at stroke onset.Methods:The patients were divided into 5 groups according to the direction of the hematoma. For each group, Spearman's correlation coefficients were calculated to investigate the relationship between hematoma volume and motor outcomes. Motor outcomes were assessed using the motor items of Stroke Impairment Assessment Set, which are impairment indexes for the distal and proximal functions of the upper and lower extremities after stroke.Results:Hematoma volume was significantly correlated with all the motor items in the group whose hematoma extended to the posterior limb of the internal capsule alone (Bonferroni correctedP<.05). On the other hand, significant correlations between hematoma volume and motor outcomes could not be found in almost all the other groups.Conclusions:Motor outcome after putaminal hemorrhage can be predicted by evaluating the progression of hematoma to the corticospinal tract and its volume using CT images at stroke onset.