Erinacol (cyatha-3,12-dien-14β-ol) and 11-O-acetylcyathin A3, new cyathane metabolites from an erinacine Q-producing Hericium erinaceum
Erinacol (cyatha-3,12-dien-14β-ol) and 11-O-acetylcyathin A3, new cyathane metabolites from an erinacine Q-producing Hericium erinaceum
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DOI：
10.1271/bbb.68.1786
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发表时间：
2004-08-01
影响因子：
1.6
通讯作者：
Sassa, T
中科院分区：
文献类型：
--
作者：
Kenmoku, H;Tanaka, K;Sassa, T
在我们寻找与猴头菌中erinacine Q生物合成相关的新的杯赛烷代谢物的过程中，我们从菌丝体提取物中分离出一种新的杯赛-3，12-二烯-14 β-醇，命名为erinacol，以及已知的11-O-乙酰杯赛三醇（erinacine Q糖苷配基）和新的代谢物11-O-乙酰杯赛素A（3）。通过光谱方法确定了每个化合物的结构。从这些代谢产物的结构特征讨论了它们之间可能的生物合成关系。
In our search for new cyathane metabolites related to the biosynthesis of erinacine Q in Hericium erinaceum, we isolated a novel cyatha-3,12-dien-14beta-ol named erinacol together with known 11-O-acetylcyathatriol (the erinacine Q aglycon) and new metabolite 11-O-acetylcyathin A(3) from the mycelial extract. The structure of each compound was determined by spectral methods. Possible biosynthetic relationships of these metabolites are discussed from their structural features.