Attitudes Toward a Potential SARS-CoV-2 Vaccine A Survey of US Adults
Attitudes Toward a Potential SARS-CoV-2 Vaccine A Survey of US Adults
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DOI：
10.7326/m20-3569
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发表时间：
2020-12-15
影响因子：
39.2
通讯作者：
Mazor, Kathleen M.
中科院分区：
文献类型：
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作者：
Fisher, Kimberly A.;Bloomstone, Sarah J.;Mazor, Kathleen M.
背景：2019冠状病毒病（COVID-19）迅速引发了全球大流行。疫苗开发正以前所未有的速度进行。一旦可用，最大限度地提高疫苗接种率和覆盖率将非常重要。目的：评估美国成年人代表性样本中接种COVID-19疫苗的意图，并确定疫苗犹豫的预测因素和原因。设计：横断面调查，于2020年4月16日至20日进行。设置：居住在美国的成年人代表性样本。参与者：从AmeriSpeak基于概率的研究小组中抽取了大约1000名成年人，覆盖了大约97%的美国家庭人口。测量：接种COVID-19疫苗的意愿通过以下问题进行测量：“当冠状病毒疫苗可用时，你会接种吗？回答选项有“是“、“否”和“不确定”。回答“不”或“不确定”的参与者被要求提供原因。结果：共有991名AmeriSpeak小组成员回答。总体而言，57.6%的参与者（n = 571）打算接种疫苗，31.6%（n = 313）不确定，10.8%（n = 107）不打算接种疫苗。与疫苗犹豫（回答“否”或“不确定”）独立相关的因素包括年龄较小、黑人、教育程度较低以及前一年未接种流感疫苗。疫苗犹豫的原因包括疫苗的具体问题，需要更多的信息，反疫苗接种的态度或信念，缺乏trust.Limitations：参与者的接种疫苗的意图进行了探讨之前，疫苗是可用的，当流行病影响美国的一个狭窄的地带。不包括有关可能增加疫苗接种接受度的特定信息或因素的问题。调查应答率为16.1%。结论：在冠状病毒大流行期间进行的这项全国性调查显示，大约十分之三的成年人不确定他们是否会接受疫苗接种，十分之一的人不打算接种COVID-19疫苗。当COVID-19疫苗可用时，需要有针对性和多管齐下的努力来提高对COVID-19疫苗的接受度。
Background: Coronavirus disease 2019 (COVID-19) has rapidly instigated a global pandemic. Vaccine development is proceeding at an unprecedented pace. Once available, it will be important to maximize vaccine uptake and coverage.Objective: To assess intent to be vaccinated against COVID-19 among a representative sample of adults in the United States and identify predictors of and reasons for vaccine hesitancy.Design: Cross-sectional survey, fielded from 16 through 20 April 2020.Setting: Representative sample of adults residing in the United States.Participants: Approximately 1000 adults drawn from the AmeriSpeak probability-based research panel, covering approximately 97% of the U.S. household population.Measurements: Intent to be vaccinated against COVID-19 was measured with the question, "When a vaccine for the coronavirus becomes available, will you get vaccinated?" Response options were "yes," "no," and "not sure." Participants who responded "no" or "not sure" were asked to provide a reason.Results: A total of 991 AmeriSpeak panel members responded. Overall, 57.6% of participants (n = 571) intended to be vaccinated, 31.6% (n = 313) were not sure, and 10.8% (n = 107) did not intend to be vaccinated. Factors independently associated with vaccine hesitancy (a response of "no" or "not sure") included younger age, Black race, lower educational attainment, and not having received the influenza vaccine in the prior year. Reasons for vaccine hesitancy included vaccine-specific concerns, a need for more information, antivaccine attitudes or beliefs, and a lack of trust.Limitations: Participants' intent to be vaccinated was explored before a vaccine was available and when the pandemic was affecting a narrower swath of the United States. Questions about specific information or factors that might increase vaccination acceptance were not included. The survey response rate was 16.1%.Conclusion: This national survey, conducted during the coronavirus pandemic, revealed that approximately 3 in 10 adults were not sure they would accept vaccination and 1 in 10 did not intend to be vaccinated against COVID-19. Targeted and multipronged efforts will be needed to increase acceptance of a COVID-19 vaccine when one becomes available.