Proliferations of the sarcoplasmic reticulum and the T system in denervated muscle fibers
Proliferations of the sarcoplasmic reticulum and the T system in denervated muscle fibers
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去神经肌纤维中肌浆网和 T 系统的增殖
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
Z. Gori
中科院分区：
文献类型：
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作者：
Z. Gori
辣根过氧化物酶已被用作示踪剂，用来证明失神经肌肉纤维中存在特殊结构、迷路的小管和池板层的形成。迷路在失神经支配后较早出现，随着萎缩的进展，迷路的数目增加。过氧化物酶反应产物有规律地填充这些结构的管腔以及三联体的中心成分。因此，迷路必须被认为是T系统的增殖。在长时间的失神经支配(30天或更长时间)后，可以在肌肉纤维中观察到板层或“螺旋复合体”的形成。它们表现为脑池的平行排列，起源于三联体的侧部。它们的管腔中没有显示任何过氧化物酶产物。目前的发现与以下观点有关：在失神经萎缩期间，两个系统，S.R.和T，都增殖形成了特有的结构。
SummaryThe horseradish peroxidase has been used as tracer to evidenciate the derivation of peculiar structures, labyrinths of tubules and lamellar formations of cisternae, present in denervated muscle fibers.The labyrinths appear early after denervation and increase in number with the progressing of atrophy. The peroxidase reaction product fills regularly the lumen of these structures as well as the central element of the triad. The labyrinths, therefore, must be regarded as a proliferation of the T-system.The lamellar formations or “helical complexes” are observed in muscle fibers after long periods of denervation (30 or more days). They appear as parallel arrays of cisternae and originate from the lateral element of the triad. They do not show any peroxidase product in their lumen.The present findings are discussed in relation to the idea that during the denervation atrophy both systems, S.R. and the T, proliferate forming characteristic structures.