The influence of chronic kidney disease and age on revascularization rates and outcomes in acute myocardial infarction - a cohort study
The influence of chronic kidney disease and age on revascularization rates and outcomes in acute myocardial infarction - a cohort study
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DOI：
10.1177/2048872616640995
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发表时间：
2017-06-01
影响因子：
4.1
通讯作者：
Gallagher, Martin
中科院分区：
文献类型：
--
作者：
Kotwal, Sradha;Ranasinghe, Isuru;Gallagher, Martin
背景资料：关于慢性肾脏疾病、年龄及其对急性心肌梗死管理和结局的影响之间复杂相互作用的数据很少。（占澳大利亚人口的32.3%）用于识别所有主要诊断为急性心肌梗死的患者（ICD 10代码：I21.0-I21.4）。患者与国家死亡登记处联系，并随访至死亡或随访结束（2009年12月31日）。慢性肾脏疾病定义为存在65种慢性肾脏疾病ICD 10诊断代码中的任何一种。主要结果是接受血运重建，住院时间和死亡率调整年龄，合并症和以前的血运重建presentation.Results：在40,472例急性心肌梗死患者中，慢性肾脏疾病存在于4814例（11.9%）。中位随访时间为2.8年（范围0-5.5年）。在多变量模型中，慢性肾脏疾病和年龄之间存在显著的相互作用（p
Background: There is a paucity of data on the complex interaction between chronic kidney disease, age and its impact on management and outcomes in acute myocardial infarction.Methods: A state based claims dataset that collects data on all hospitalizations (representing 32.3% of the Australian population) was used to identify all patients admitted with a principal diagnosis of acute myocardial infarction (ICD10 codes: I21.0-I21.4) over a four-year period. Patients were linked to the state death registry and followed until death or end of follow-up (31 December 2009). Chronic kidney disease was defined as the presence of any of 65 ICD10 diagnostic codes for chronic kidney disease. The primary outcomes were receipt of revascularization, length of hospital stay and mortality adjusted for age, comorbidities and prior revascularization at presentation.Results: Of the 40,472 patients with acute myocardial infarction, chronic kidney disease was present in 4814 patients (11.9%). Median follow-up was 2.8 years (range 0-5.5 years). In the multivariable model, there was a marked interaction between chronic kidney disease and age (p