Determination of kerosene and light oil components in blood.
Determination of kerosene and light oil components in blood.
复制标题
血液中煤油和轻油成分的测定。
DOI：
10.1002/bms.1200200810
复制
发表时间：
1991
期刊：
影响因子：
--
通讯作者：
K. Hara
中科院分区：
文献类型：
--
作者：
K. Kimura;T. Nagata;K. Kudo;T. Imamura;K. Hara
建立了一种快速、灵敏的测定煤油或轻油蒸气染毒大鼠血液中燃料成分的毛细管气相色谱/质谱法。采用顶空法结合盐析技术，在暴露于煤油或轻油蒸气的大鼠血液中清楚地检测到碳数为8-10的脂肪烃和芳烃，如甲苯、二甲苯、3-乙基甲苯和4-乙基甲苯以及三甲基苯。轻油作业者血液中偏三甲苯与甲苯的浓度比高于煤油作业者。在甲苯和偏三甲苯中的检测下限分别为50 pg和1 ng。我们的建议是，这种方法是有用的法医调查，以检测血液中的燃料成分和区分煤油和轻油的血液组织中的目的。
A sensitive and rapid method to analyse fuel components in blood from rats exposed to kerosene or light oil vapour was developed by making use of capillary gas chromatography/mass spectrometry. The aliphatic hydrocarbons with carbon numbers 8-10 and aromatics such as toluene, xylene, 3- and 4-ethyltoluene and trimethylbenzenes were clearly detected in blood from rats exposed to kerosene or light oil vapour, using the head-space method combined with the salting-out technique. The concentration ratio of pseudocumene to toluene in blood exposed to light oil was higher than that in the case of exposure to kerosene. The lower limits of detection were 50 pg and 1 ng in toluene and pseudocumene, respectively. Our suggestion is that this method is useful in forensic investigations to detect fuel components in blood and for the purposes of differentiating kerosene and light oil in blood tissues.