Cochlear efferent innervation and function.
Cochlear efferent innervation and function.
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DOI：
10.1097/moo.0b013e32833e05d6
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发表时间：
2010-10
影响因子：
1.6
通讯作者：
Guinan JJ Jr
中科院分区：
文献类型：
--
作者：
Guinan JJ Jr
本文综述了2009年至2010年初有关橄榄耳蜗传出神经解剖和功能的新发现。在审查期间的工作增加了我们的理解内侧传出（MOC）机制外毛细胞，MOC反射调谐，MOC效应失真产品耳声发射，MOC效应的时间过程中，MOC效应在心理物理测试和理解语音，MOC效应在注意力和学习，和双耳听力的外侧传出功能。此外，传出神经的分子机制及其对耳蜗发育的影响也有了新的认识。使用耳声发射测量传出效应的技术现在已经发展得很好，并且在临床应用中有希望，从预测哪些受试者容易受到声创伤到表征传出激活和学习障碍之间的关系。为了实现这一承诺，需要进行研究，以高标准应用这些技术。
This review covers topics relevant to olivocochlear-efferent anatomy and function for which there are new findings in papers from 2009 to early 2010. Work within the review period has increased our understanding of medial efferent (MOC) mechanisms in outer hair cells, MOC reflex tuning, MOC effects on distortion product otoacoustic emissions, the time course of MOC effects, MOC effects in psychophysical tests and on understanding speech, MOC effects in attention and learning, and lateral efferent function in binaural hearing. In addition, there are new insights into efferent molecular mechanisms and their effect on cochlear development. Techniques for measuring efferent effects using otoacoustic emissions are now well developed and have promise in clinical applications ranging from predicting which subjects are susceptible to acoustic trauma to characterizing relationships between efferent activation and learning disabilities. To realize this promise, studies are needed in which these techniques are applied with high standards.