Large sequence polymorphisms classify Mycobacterium tuberculosis strains with ancestral spoligotyping patterns
Large sequence polymorphisms classify Mycobacterium tuberculosis strains with ancestral spoligotyping patterns
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DOI：
10.1128/jcm.00828-07
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发表时间：
2007-10-01
影响因子：
9.4
通讯作者：
Gagneux, Sebastien
中科院分区：
文献类型：
--
作者：
Flores, Laura;Van, Tran;Gagneux, Sebastien
基因组缺失分析显示，结核分枝杆菌菌株表现出几乎所有间隔区存在的间隔区寡核苷酸分型模式，要么属于包括W-北京菌株家族的菌株谱系，要么属于M.结核
Genomic deletion analysis revealed that strains of Mycobacterium tuberculosis exhibiting spoligotyping patterns with almost all spacers present belong either to a strain lineage that includes the W-Beijing strain family or to the ancestral strain lineage of M. tuberculosis.