THE CENTRAL VAGAL EFFERENT SUPPLY TO THE ESOPHAGUS AND LOWER ESOPHAGEAL SPHINCTER OF THE CAT
THE CENTRAL VAGAL EFFERENT SUPPLY TO THE ESOPHAGUS AND LOWER ESOPHAGEAL SPHINCTER OF THE CAT
复制标题
DOI：
10.1016/0016-5085(93)90352-d
复制
发表时间：
1993-05-01
期刊：
影响因子：
29.4
通讯作者：
DIAMANT, NE
中科院分区：
文献类型：
--
作者：
COLLMAN, PI;TREMBLAY, L;DIAMANT, NE
背景：对支配食管平滑肌的中枢传出神经元知之甚少。本研究的目的是定义的脑干吞咽机制的猫，特别是那些供应食管体smoothmuscles.Methods的传出神经通路的位置：荧光，逆行运输示踪剂被注入到颈部横纹肌和胸平滑肌段的食管，也下食管sphincter.Results：横纹肌传出被发现在吻侧疑核，但约8%位于迷走神经背核。平滑肌传出存在于迷走神经背侧运动核在两组，一个吻侧和尾侧的obex。在疑后核中发现了另外一组。大约8%的总平滑肌传出存在于疑核的吻侧和横纹肌传出的外侧。食管下括约肌传出神经的分布与平滑肌传出神经的分布相似，但迷走神经背核的细胞浓度向尾侧偏移。结论：食管体部平滑肌运动神经元的分布与支配食管下括约肌的神经元的分布相似，但存在一定的地形变异。
Background:Little is Known of the central efferent neurons innervating the smooth muscle esophagus. The aim of this study was to define the location of the efferent neural pathways of the brain stem swallowing mechanism in the cat, particularly those supplying the esophageal body smooth muscle.Methods:Fluorescent, retrogradely transported tracers were injected into the cervical striated muscle and thoracic smooth muscle segments of the esophagus and also the lower esophageal sphincter.Results:Striated muscle efferents were found in the rostral nucleus ambiguus, but approximately 8% were located in the dorsal motor vagal nucleus. Smooth muscle efferents were present in the dorsal motor vagal nucleus in two groups, one rostral and one caudal to the obex. An additional group was found in nucleus retroambiguus. Approximately 8% of the total smooth muscle efferents were present in rostral nucleus ambiguus and were lateral to the striated muscle efferents. The lower esophageal sphincter efferents had a similar distribution to the smooth muscle efferents, but the rostral concentration of cells in the dorsal motor vagal nucleus was shifted caudally.Conclusions:Esophageal body smooth muscle motoneurons are arranged with a similar distribution to those innervating the lower esophageal sphincter but with some topographic variation.