Resorbable collagen membranes: histopathologic features
Resorbable collagen membranes: histopathologic features
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DOI：
10.1016/j.oooo.2014.04.006
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发表时间：
2014-08-01
影响因子：
2.9
通讯作者：
Woo, Sook-Bin
中科院分区：
文献类型：
--
作者：
Almazrooa, Soulafa A.;Noonan, Vikki;Woo, Sook-Bin
目标。可吸收胶原膜（RCMs）通常被口腔外科医生、牙周病医生和牙髓医生用于多种目的。我们报告了6例未像预期那样再吸收的rcm，并描述了其组织病理特征。研究设计。在骨活检标本中发现了不寻常的纤维状异物。苏木精-伊红和马松三色染色。与临床医生联系以获取详细的临床信息。有三男三女。rcm表现为透明化、细胞少、细腻的嗜酸性原纤维或网状结构，无异物反应。它们是可折射的，如预期的那样被染色为马松三色。3例rcm持续时间超过预期（2-6周），5例可能延缓愈合。虽然RCM被认为是相当快的可吸收性，但这种材料有时会在伤口部位持续存在，没有任何明显的异物反应，可能会延缓愈合。
Objective. Resorbable collagen membranes (RCMs) are commonly used by oral surgeons, periodontists, and endodontists for multiple purposes. We report 6 cases of RCMs that did not resorb as expected and describe the histopathologic features.Study Design. Cases of an unusual fibrillar foreign material were noted in biopsy specimens curetted from bone. Hematoxylin-eosin and Masson trichrome stains were performed. Clinicians were contacted for detailed clinical information.Results. There were 3 men and 3 women. RCMs presented as hyalinized, paucicellular, delicate eosinophilic fibrils or a meshwork without a foreign body reaction. They were refractile and stained for Masson trichrome as expected. These RCMs persisted longer than expected (2-6 weeks) in 3 cases and may have retarded healing in 5 cases.Conclusions. Although RCM is supposed to be fairly rapidly resorbable, this material sometimes persists within wound sites without any obvious foreign body reaction and may retard healing.