Conditions for Highly Efficient and Reproducible Round-Window Stimulation in Humans

Conditions for Highly Efficient and Reproducible Round-Window Stimulation in Humans
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DOI:
10.1159/000333807
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发表时间:
2012-01-01
影响因子:
1.6
通讯作者:
Dalhoff, Ernst
Dalhoff, Ernst
中科院分区:
医学3区
文献类型:
--
作者:
Schraven, Sebastian P.;Hirt, Bernhard;Dalhoff, Ernst

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圆窗刺激是一种应用于中耳植入的新方法。为了探讨影响圆窗刺激效率的因素,在6个人颞骨上进行了不同驱动器几何形状和耦合条件的实验。实验结果表明,采用直径1.0 mm、尖端呈30度倾斜几何形状的杆和附着硅衬垫时,执行器的振幅比与圆窗执行器的振幅比最有效。在这种情况下,振幅比为0.34频率高达1.5 kHz和0.27频率高达20 kHz,与标准偏差只有4-6分贝在大多数频率。本文和另一篇论文的数据分析表明,控制适当的圆窗膜预紧力以及倾斜尖端的几何形状是最大性能的主要要求。巴塞尔S. Karger股份有限公司版权所有
Round-window stimulation is a new clinical approach for the application of active middle-ear implants. To investigate factors influencing the efficiency of round-window stimulation, experiments in 6 human temporal bones were performed with different actuator geometries and coupling conditions. The experiments show that the amplitude ratio between stapes and round-window actuator vibration is most efficient when using a 1.0-mm diameter rod with a 30 inclined tip geometry and an attached silicone pad. In this case, the amplitude ratio is 0.34 for frequencies up to 1.5 kHz and 0.27 for frequencies up to 20 kHz, with a standard deviation of only 4-6 dB at most frequencies. The analysis of data presented here and in a companion paper suggests that control of proper round-window membrane pretension as well as the inclined tip geometry are the major requirements for maximal performance. Copyright (C) 2011 S. Karger AG, Basel