Drastic elevations in mortality among female injection drug users in a Canadian setting
Drastic elevations in mortality among female injection drug users in a Canadian setting
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DOI：
10.1080/09540120500159292
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发表时间：
2006-02-01
影响因子：
1.7
通讯作者：
Wood, E
中科院分区：
文献类型：
--
作者：
Spittal, PM;Hogg, RS;Wood, E
居住在温哥华市中心东区的妇女的健康和社会状况最近成为国际社会关注的焦点。由于很少有研究探讨率和相关的死亡成瘾妇女在加拿大，我们的特点是女性注射吸毒者（IDUs）在温哥华的死亡率模式。温哥华注射吸毒者研究（VIDUS）是一项针对注射吸毒者的前瞻性开放队列研究。本文所述分析仅限于1996年5月至2002年5月期间入组的14岁或以上女性。我们使用Kaplan-Meier方法估计累积死亡率，并使用考克斯回归计算单变量和调整后的相对风险。1996年5月至2002年5月，从温哥华地区招募了520名女性注射吸毒者，其中68人在研究期间死亡。在报告基线性交易参与的人、基线HIV感染者和基线居住在不稳定住房中的人中观察到死亡率升高（所有对数秩：p < 0.05）。在校正分析中，HIV感染（RH = 3.09 [95%CI：1.86 - 5.11]; p
The health and social conditions of women living in Vancouver's Downtown Eastside has recently been the focus of substantial international attention. Since few studies have examined rates and correlates of death among addicted women in Canada, we have characterized patterns of mortality among female injection drug users (IDUs) in Vancouver. The Vancouver Injection Drug Users Study (VIDUS) is a prospective open cohort study of IDUs. The analyses presented here, were restricted to women enrolled between May 1996 and May 2002 and who were aged 14 years or older. We estimated cumulative mortality rates using Kaplan-Meier methods and Cox regression was used to calculate univariate and adjusted relative hazards. Between May 1996 and May 2002, 520 female IDUs have been recruited from the Vancouver area among whom 68 died during the study period. Elevated rates of mortality were observed among those who reported, baseline sex-trade involvement, those with HIV-infection at baseline, and those who lived in unstable housing at baseline (all log-rank: p < 0.05). In adjusted analyses, HIV infection (RH = 3.09 [95% CI: 1.86 - 5.11]; p