Pre-anesthetic maternal separation increases pups' locomotor behavior during emergence from anesthesia in rats.
Pre-anesthetic maternal separation increases pups' locomotor behavior during emergence from anesthesia in rats.
复制标题
麻醉前母体分离会增加大鼠麻醉苏醒期间幼仔的运动行为。
DOI：
10.1111/j.0001-5172.2004.00290.x
复制
发表时间：
2004
影响因子：
2.1
通讯作者：
Al-Chaer,ED
中科院分区：
文献类型：
--
作者：
Arai,Y-CP;Ueda,W;Al-Chaer,ED
背景：儿童麻醉苏醒后的问题行为，部分与产妇分离有关，是儿科麻醉的主要问题。在人类以及许多其他哺乳动物中，这种分离会导致心理和行为上的变化。本研究旨在探讨麻醉前母体分离对大鼠幼鼠是否有类似的影响。方法：以66只3周龄的雄性大鼠为实验对象。将大鼠分为两组；有水坝的幼崽（n= 33）和没有水坝的幼崽（n= 33）。用1.2%氟烷麻醉幼崽30分钟。之后，我们用视频跟踪系统记录了他们全身麻醉后的运动行为。结果：麻醉前母鼠分离显著增加了仔鼠出胎时的最大速度和移动距离。结论：麻醉前母鼠分离影响了幼鼠的运动行为。
Background:Problematic behavior at emergence from anesthesia in children, partly linked with maternal separation, is a major problem in pediatric anesthesia. In humans, as well as in many other mammalian species, such separation causes psychological and behavioral changes. This study was to investigate whether or not pre‐anesthetic maternal separation has a similar effect on rat pups.Methods:This study was conducted on 66 3‐week‐old Sprague–Dawley male rats. The rats were divided into two groups; pups housed with a dam (n= 33) and those housed without (n= 33). Pups were anesthetized with 1.2% halothane for 30 min. Afterwards we recorded their locomotor behavior at emergence from general anesthesia using a video tracking system.Results:Pre‐anesthetic maternal separation significantly increased the maximum velocity and the distance traveled by pups at the emergence.Conclusion:Pre‐anesthetic maternal separation influenced pups' locomotive behavior at emergence.