THE RELATIONSHIP BETWEEN CHRONOLOGICAL AGE AND THE ERYTHEMAL RESPONSE TO ULTRAVIOLET-B RADIATION
THE RELATIONSHIP BETWEEN CHRONOLOGICAL AGE AND THE ERYTHEMAL RESPONSE TO ULTRAVIOLET-B RADIATION
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DOI：
10.1111/j.1365-2133.1992.tb00671.x
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发表时间：
1992-04-01
影响因子：
10.3
通讯作者：
FARR, PM
中科院分区：
文献类型：
--
作者：
COX, NH;DIFFEY, BL;FARR, PM
为了研究红斑对紫外线辐射的反应是否随年龄变化，我们回顾了成人和儿童的单色仪光测试结果，并测量了另外38名受试者对UVB红斑的剂量-反应曲线。成人与儿童300 nm最小红斑量(MED)差异无统计学意义，254例成人最小红斑量为34MJ/cm2(14~80MJ/cm2)，24例15岁以下儿童最小红斑量为30MJ/cm2(10~80MJ/cm2)。目的对15名25岁以下人群和23名60岁以上人群进行UVB诱发红斑的检测。建立了UVB红斑的剂量效应曲线，用Logit回归计算曲线最陡处的斜率：青年组大于老年组(P<；0.02)。然而，在视觉评估的MED或计算出的产生恒定程度的轻度红斑所需的UVB剂量方面，两组之间没有差异。
To investigate whether erythemal responses to ultraviolet radiation alter with age, we have reviewed the results of monochromator phototesting in adults and children, and have measured the dose-response curves for UVB erythema in a further 38 subjects. There was no significant difference between adults and children in minimal erythema dose (MED) at 300 nm; the median MED in 254 adults was 34 mJ/cm2 (range 14-80 mJ/cm2) and in 24 children aged less than 15 years was 30 mJ/cm2 (range 10-80 mJ/cm2). Objective measurements of UVB-induced erythema were performed in 15 subjects aged below 25 years and 23 subjects aged above 60 years. A dose response curve for UVB erythema was constructed for each subject and the slope of the steepest part of each curve calculated by logit regression: the values in the young subjects were greater than in the older group (P < 0.02). However, there was no difference between the two groups in either the visually assessed MED or the calculated UVB dose required to produce a constant degree of mild erythema.