Arlequin (version 3.0): An integrated software package for population genetics data analysis
Arlequin (version 3.0): An integrated software package for population genetics data analysis
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DOI：
10.1177/117693430500100003
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发表时间：
2005-01-01
影响因子：
2.6
通讯作者：
Schneider, Stefan
中科院分区：
文献类型：
--
作者：
Excoffier, Laurent;Laval, Guillaume;Schneider, Stefan
Arlequin Ver3.0是一个软件包，集成了几种基本和先进的群体遗传学数据分析方法，如标准遗传多样性指数的计算，等位基因和单倍型频率的估计，连锁平衡偏离检验，选择中性和人口平衡偏离检验，过去群体扩展的估计或参数，并在AMOVA框架下对人口细分进行深入分析。Arlequin 3引入了一个用C++编写的全新图形界面，一个更强大的输入文件语义分析，以及两个新方法：一个贝叶斯估计配子阶段的多位点基因型，和一个估计的参数的瞬时空间扩展的DNA序列多态性。Arlequin可以处理多种数据类型，例如DNA序列、微卫星数据或标准多位点基因型。该软件的Windows版本可在http://cmpg.unibe.ch/software/arlequin3上免费获得。
Arlequin ver 3.0 is a software package integrating several basic and advanced methods for population genetics data analysis, like the computation of standard genetic diversity indices, the estimation of allele and haplotype frequencies, tests of departure from linkage equilibrium, departure from selective neutrality and demographic equilibrium, estimation or parameters from past population expansions, and thorough analyses of population subdivision under the AMOVA framework. Arlequin 3 introduces a completely new graphical interface written in C++, a more robust semantic analysis of input files, and two new methods: a Bayesian estimation of gametic phase from multi-locus genotypes, and an estimation of the parameters of an instantaneous spatial expansion from DNA sequence polymorphism. Arlequin can handle several data types like DNA sequences, microsatellite data, or standard multi-locus genotypes. A Windows version of the software is freely available on http://cmpg.unibe.ch/software/arlequin3.