An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values
An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values
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DOI：
10.1186/s12961-015-0050-7
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发表时间：
2015-11-02
影响因子：
4
通讯作者：
Hur, Hannah
中科院分区：
文献类型：
--
作者：
Carter, Ashley J. R.;Delarosa, Beverly;Hur, Hannah
背景：理想情况下，每种特定类型癌症的研究资金分配应与其社会负担成比例。这种负担可以估计与度量的“年寿命损失”（YLL），结合整体死亡率和年龄在death.Methods：使用英国的数据从2010年，我们比较了研究资金从国家癌症研究所到这个YLL负担度量26种癌症，以确定癌症研究资金分配和社会负担之间的差异。我们还将这些值与美国2010年的数据和英国2005年发表的数据进行了比较。结果：我们的研究揭示了癌症研究经费和负担之间的一些差异。一些癌症（睾丸癌、白血病、霍奇金淋巴瘤、乳腺癌、宫颈癌、卵巢癌、前列腺癌）的资助水平远远高于其相对负担，而其他癌症（胆囊癌、肺癌、鼻咽癌、肠癌、胃癌、胰腺癌、甲状腺癌、食道癌、肝癌、肾癌、膀胱癌和脑/中枢神经系统癌）的资助水平似乎不足。过去十年来，联合王国的供资模式总体上转向增加对以前供资不足的癌症的供资，但有一个明显的例外，显示出匡威的趋势（乳腺癌）。英国和美国的资金模式之间的广泛关系是类似的，有几个例外（如白血病，霍奇金淋巴瘤，前列腺，睾丸癌）。结论：有癌症研究资金分配和社会负担之间的差异，在英国。这些差异在英国和美国大致相似，虽然它们似乎正在改善，但并不是所有类型的癌症都是如此。
Background: Ideally, the allocation of research funding for each specific type of cancer should be proportional to its societal burden. This burden can be estimated with the metric 'years of life lost' (YLL), which combines overall mortality and age at death.Methods: Using United Kingdom data from 2010, we compared research funding from the National Cancer Research Institute to this YLL burden metric for 26 types of cancers in order to identify the discrepancies between cancer research funding allocation and societal burden. We also compared these values to United States data from 2010 and United Kingdom data published in 2005.Results: Our study revealed a number of discrepancies between cancer research funding and burden. Some cancers are funded at levels far higher than their relative burden suggests (testicular, leukaemia, Hodgkin's lymphoma, breast, cervical, ovarian, prostate) while other cancers appear underfunded (gallbladder, lung, nasopharyngeal, intestine, stomach, pancreatic, thyroid, oesophageal, liver, kidney, bladder, and brain/central nervous system). United Kingdom funding patterns over the past decade have generally moved to increase funding to previously underfunded cancers with one notable exception showing a converse trend (breast cancer). The broad relationship between United Kingdom and United States funding patterns is similar with a few exceptions (e.g. leukaemia, Hodgkin's lymphoma, prostate, testicular cancer).Conclusions: There are discrepancies between cancer research funding allocation and societal burden in the United Kingdom. These discrepancies are broadly similar in both the United Kingdom and the United States and, while they appear to be improving, this is not consistent across all types of cancer.