Predictors and correlates of high levels of depression and anxiety symptoms among children at age 10

Predictors and correlates of high levels of depression and anxiety symptoms among children at age 10
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DOI:
10.1097/01.chi.0000184930.18552.4d
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发表时间:
2006-02-01
影响因子:
13.3
通讯作者:
Day, NL
Day, NL
中科院分区:
医学1区
文献类型:
--
作者:
Leech, SL;Larkby, CA;Day, NL

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目的:确定10岁儿童抑郁和焦虑症状的预测因素或相关因素。方法:妇女和她们的后代从产前第四个月到10年。10年时有636对母子,出生队列的随访率为83%。在每个阶段测量认知、心理、社会人口和环境因素。高度抑郁和焦虑被定义为多种症状高于每项指标的平均值1 SD。这些措施相结合,以代表高度抑郁和/或焦虑(D/A)在10岁。结果如下:产前10年D/A的预测因素是更多的母亲抑郁症状,非裔美国人种族,更少的社会支持,更大的家庭密度和产前大麻暴露。从18个月到6岁,儿童智商较低,3岁时儿童受伤,注意力问题预测了10岁时的D/A症状。在所有的研究阶段中,儿童智商较低、怀孕期间的家庭密度、注意力问题、儿童早期损伤和产前大麻暴露都是D/A的预测因素。产妇的心理和社会人口因素在最终模型中没有显着性。结论:来自妊娠期和幼儿期的因素预测了10岁时抑郁和焦虑的高症状水平。当考虑妊娠期暴露、早期环境因素和儿童特征时,母亲抑郁和社会经济状况与早发性D/A无显著相关。妊娠期暴露于维生素B1可轻微预测10岁时的抑郁/焦虑。
Objective: To identify factors that predict or are correlated with symptoms of depression and anxiety in 10-year-olds. Method: Women and their offspring were followed from the fourth prenatal month through 10 years. There were 636 mother-child pairs at 10 years, a follow-up rate of 83% of the birth cohort. Cognitive, psychological, sociodemographic, and environmental factors were measured at each phase. High depression and anxiety were defined as having a number of symptoms > 1 SD above the mean for each measure. These measures were combined to represent high depression and/or anxiety (D/A) at 10 years of age. Results: Predictors from the prenatal period of D/A at 10 years were more maternal depression symptoms, African American race, less social support, greater household density, and prenatal marijuana exposure. From 18 months through 6 years, lower child IQ, child injuries at age 3, and attention problems predicted symptoms of D/A at age 10. Across all study phases, lower child IQ, household density during pregnancy, attention problems, early childhood injuries, and prenatal marijuana exposure predicted D/A. Maternal psychological and sociodemographic factors were not significant in the final model. Conclusions: Factors from gestation and early childhood predict high symptom levels of depression and anxiety at age 10. When gestational exposure, early environmental factors, and child characteristics were considered, maternal depression and socioeconomic status were not significantly associated with early onset D/A. Marijuana exposure during gestation marginally predicted depression/anxiety at age 10.