Retrospective survey of Chikungunya disease in Reunion Island hospital staff
Retrospective survey of Chikungunya disease in Reunion Island hospital staff
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DOI：
10.1017/s0950268807008424
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发表时间：
2008-02-01
影响因子：
4.2
通讯作者：
Michault, A.
中科院分区：
文献类型：
--
作者：
Staikowsky, F.;Le Roux, K.;Michault, A.
留尼汪岛（印度洋）自2005年2月以来首次出现已知的基孔肯雅病毒流行。为了更好地了解这种疾病，为医院工作人员及其家属起草了一份调查问卷。被研究的人口中约有三分之一感染了CHIKV病毒，这一比例随着年龄的增长而增加，在妇女中比例更高。花园的存在与CHIKV感染有关。病例地理分布与病媒白纹伊蚊分布基本一致。主要临床表现为关节痛、发热。34.4%的病例完全康复，55.6%的病例复发，10%的病例慢性复发。在95%的病例中，扑热息痛被用作止痛药，有时与非甾体抗炎药、皮质激素或传统草药联合使用。调查提供了关于有利于传播的因素、临床症状、复发的重要性和所使用的治疗方法的宝贵信息。
Reunion Island (Indian Ocean) has been suffering from its first known Chikungunya virus (CHIKV) epidemic since February 2005. To achieve a better understanding of the disease, a questionnaire was drawn up for hospital staff members and their household. CHIKV infected about one-third of the Studied population, the proportion increasing with age and being higher in women. Presence of a garden was associated with CHIKV infection. The geographical distribution of cases was concordant with insect vector Aedes albopictus distribution. The main clinical signs were arthralgia and fever. The disease evolved towards full recovery in 34.4 % of cases, a relapse in 55.6 %, or a chronic form in 10 %. Paracetamol was used as a painkiller in 95 % of cases, sometimes associated with non-steroidal anti-inflammatory drugs, corticolds, or traditional herbal medicine. The survey provided valuable information on the factors that favour transmission, the clinical signs, the importance of relapses and the therapies used.