Assessment of functional sit-to-stand muscle power: Cross-sectional trajectories across the lifespan
Assessment of functional sit-to-stand muscle power: Cross-sectional trajectories across the lifespan
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DOI：
10.1016/j.exger.2021.111448
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发表时间：
2021-06-11
影响因子：
3.9
通讯作者：
Suetta, Charlotte
中科院分区：
文献类型：
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作者：
Alcazar, Julian;Aagaard, Per;Suetta, Charlotte
背景资料：30-s坐-站（STS）肌力测试是评估老年人肌力的有效测试;然而，它是否可以用于评估成人寿命中下肢肌力的轨迹尚不清楚。本研究评估了在整个生命周期中相对、异速生长和特定STS肌肉力量变化的模式和时间过程。方法：受试者参加哥本哈根肌肉减少症研究（729名女性和576名男性;年龄20至93岁）。下肢肌力采用30秒版STS肌力测试进行评估。将异速生长、相对和特定STS功效计算为绝对STS功效，其分别标准化为通过DXA评估的身高平方、体重和腿部瘦体重。结果如下：女性的相对STS肌肉力量倾向于增加（0.08 +/- 0.05 W中心点kg- 1中心点yr- 1; p = 0.082），男性增加（0.14 +/- 0.07 W中心点kg- 1中心点yr- 1; p = 0.046）20 - 30岁，随后缓慢下降30 - 50岁之间（分别为-0.05 +/- 0.05 W中心点kg- 1中心点yr- 1和-0.06 +/- 0.08 W中心点kg- 1中心点yr- 1;均p > 0.05）。然后，相对STS功率以加速的速率下降，直到男性（-0.09 +/- 0.02 W中心点kg- 1中心点yr- 1）和女性直到75岁（-0.09 +/- 0.01 W中心点kg- 1中心点yr- 1）（均p < 0.001）。在75岁及以上的女性中观察到较低的下降率（-0.04 +/- 0.02 W中心点kg- 1中心点yr- 1; p = 0.039）。异速生长和特异性STS功率也有类似的年龄相关模式。结论：STS肌肉力量测试似乎提供了一个可行的和廉价的工具，以监测整个寿命的肌肉力量的横截面轨迹。
Background: The 30-s sit-to-stand (STS) muscle power test is a valid test to assess muscle power in older people; however, whether it may be used to assess trajectories of lower-limb muscle power through the adult lifespan is not known. This study evaluated the pattern and time course of variations in relative, allometric and specific STS muscle power throughout the lifespan. Methods: Subjects participating in the Copenhagen Sarcopenia Study (729 women and 576 men; aged 20 to 93 years) were included. Lower-limb muscle power was assessed with the 30-s version of the STS muscle power test. Allometric, relative and specific STS power were calculated as absolute STS power normalized to height squared, body mass and leg lean mass as assessed by DXA, respectively. Results: Relative STS muscle power tended to increase in women (0.08 +/- 0.05 W center dot kg- 1 center dot yr- 1; p = 0.082) and increased in men (0.14 +/- 0.07 W center dot kg- 1 center dot yr- 1; p = 0.046) between 20 and 30 years, followed by a slow decline (-0.05 +/- 0.05 W center dot kg- 1 center dot yr- 1 and -0.06 +/- 0.08 W center dot kg- 1 center dot yr- 1, respectively; both p > 0.05) between 30 and 50 years. Then, relative STS power declined at an accelerated rate up to oldest age in men (-0.09 +/- 0.02 W center dot kg- 1 center dot yr- 1) and in women until the age of 75 (-0.09 +/- 0.01 W center dot kg- 1 center dot yr- 1) (both p < 0.001). A lower rate of decline was observed in women aged 75 and older (-0.04 +/- 0.02 W center dot kg- 1 center dot yr- 1; p = 0.039). Similar age-related patterns were noted for allometric and specific STS power. Conclusions: The STS muscle power test appears to provide a feasible and inexpensive tool to monitor crosssectional trajectories of muscle power throughout the lifespan.