Epidemiologic study on penile cancer in Brazil
Epidemiologic study on penile cancer in Brazil
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DOI：
10.1590/s1677-55382008000500007
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发表时间：
2008-10-01
影响因子：
3.7
通讯作者：
Glina, Sidney
中科院分区：
文献类型：
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作者：
Favorito, Luciano A.;Nardi, Aguinaldo C.;Glina, Sidney
目标。为了解巴西阴茎癌的流行病学特征。材料与方法2006年5月至2007年6月，向所有巴西泌尿科医生发放了一份调查问卷。分析患者的临床和流行病学资料(年龄、种族、居住地、性传播病史、吸烟、包皮环切术、医院服务类型)，以及症状出现到诊断的时间、肿瘤的病理特征(组织学类型、程度、病变部位和大小、疾病分期)、治疗类型和患者的现状。巴西记录了283例新的阴茎癌病例。这些病例大多发生在北部和东北部(53.02%)和东南部(45.54%)地区。年龄在46岁以上者占78.96%(224例)，35岁以下者仅21例(7.41%)。在283例表现为阴茎癌的患者中，171例(60.42%)有包茎，因此不可能暴露龟头。在283例患者中，18例(6.36%)既往HPV感染病史为阳性。101例(35.68%)有吸烟史。绝大多数病例(n=207，73.14%)的肿瘤位于龟头和包皮。肿瘤累及龟头、包皮和阴茎48例(16.96%)，累及整个阴茎28例(9.89%)，大多数患者(n=123；75.26%)表现为T1或T2，仅9例(3.18%)表现为T4病变。结论阴茎癌在巴西是一种非常常见的病理类型，主要影响居住在巴西北部和东北部的低收入白人未割包皮患者。
Objectives. To assess epidemiologic characteristics of penile cancer in Brazil.Materials and Methods From May 2006 to June 2007, a questionnaire was distributed to all Brazilian urologists. Their patients' clinical and epidemiological data was analyzed (age, race, place of residence, history of sexually transmitted diseases, tobacco smoking, performance of circumcision, type of hospital service), as well as the time between the appearance of the symptoms and the diagnosis, the pathological characteristics of the tumor (histological type, degree, localization and size of lesion, stage of disease), the type of treatment performed and the present state of the patientResults. 283 new cases of penile cancer in Brazil were recorded. The majority of these cases occurred in the north and northeast (53.02%) and southeast (45.54%) regions. The majority of patients (224, or 78.96%) were more than 46 years of age while only 21 patients (7.41%) were less than 35 years of age. Of the 283 patients presenting penile cancer, 171 (60.42%) had phimosis with the consequent impossibility to expose the glans. A prior medical history positive for HPV infection was reported in 18 of the 283 cases (6.36%). In 101 patients (35.68%) tobacco smoking was reported. The vast majority of the cases (n = 207, 73.14%) presented with tumors localized in the glans and prepuce. In 48 cases (16 96%) the tumor affected the glans, the prepuce and the corpus penis; in 28 cases (9.89%) the tumor affected the entire penis The majority of the patients (n = 123; 75.26%) presented with T1 or T2, only 9 patients (3.18%) presented with T4 disease.Conclusion Penile cancer is a very frequent pathology in Brazil, predominantly affecting low income, white, uncircumcised patients, living in the north and northeast regions of the country.