Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles.: Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds
Ruthenium-catalyzed C-H/CO/olefin coupling reaction of N-arylpyrazoles.: Extraordinary reactivity of N-arylpyrazoles toward carbonylation at C-H bonds
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DOI：
10.1021/jo0343127
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发表时间：
2003-09-19
影响因子：
3.6
通讯作者：
Murai, S
中科院分区：
文献类型：
--
作者：
Asaumi, T;Chatani, N;Murai, S
在Ru-3（CO）（12）存在下，1-芳基吡唑与CO和乙烯的反应导致邻位C-H键的区域选择性羰基化。虽然发现吡唑环也用作C-H键断裂的导向基团，但反应的效率取决于吡唑环的位置。
The reaction of 1-arylpyrazoles with CO and ethylene in the presence of Ru-3(CO)(12) resulted in regioselective carbonylation at the ortho C-H bonds. While it is found that the pyrazole ring also functions as the directing group for C-H bond cleavage, the efficiency of the reaction depends on the position of the pyrazole ring.