Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis
Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis
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DOI：
10.2337/diabetes.49.9.1601
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发表时间：
2000-09-01
期刊：
影响因子：
7.7
通讯作者：
Groop, LC
中科院分区：
文献类型：
--
作者：
Gu, HF;Almgren, P;Groop, LC
We studied whether there is an association between the single nucleotide polymorphism c.533A>C (K121Q) in the glycoprotein PC-1 gene and features of the metabolic syndrome in case-control and intrafamily association studies in 922 subjects from Finland and Sweden. No difference was observed in the Q allele frequency between control subjects and type 2 diabetic subjects (12.9 vs. 15.1%), The QK genotype was associated with higher fasting plasma glucose (FPG) concentrations than the WC genotype in type 2 diabetic patients (P
