A STUDY OF VITAMIN-D LEVELS IN INDONESIAN PATIENTS WITH UNTREATED PULMONARY TUBERCULOSIS
A STUDY OF VITAMIN-D LEVELS IN INDONESIAN PATIENTS WITH UNTREATED PULMONARY TUBERCULOSIS
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DOI：
10.1016/0041-3879(85)90035-2
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发表时间：
1985-01-01
期刊：
影响因子：
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通讯作者：
KARDJITO, T
中科院分区：
文献类型：
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作者：
GRANGE, JM;DAVIES, PDO;KARDJITO, T
血清维生素D水平，测量25-羟胆钙化醇（25-OHD 3），40例印度尼西亚肺结核患者和38名健康对照组非常相似。在两组中，血清25-OHD 3水平的分布是双峰的，约四分之一的个体属于具有较高水平的组。有一种趋势，在这组中的控制是结核菌素阴性和患者在这组中有较少的广泛活动性肺部疾病。虽然还不确定这种关联是否是由于维生素D对保护性免疫反应的直接影响，但将这种维生素用作抗结核治疗的辅助药物值得考虑。
The levels of serum vitamin D, measured as 25-hydroxycholecalciferol (25-OHD3), among 40 Indonesian patients with pulmonary tuberculosis and 38 healthy controls were very similar. In both groups the distribution of the serum 25-OHD3 levels were bimodal with about a quarter of the individuals belonging to the group with higher levels. There was a tendency for controls in this group to be tuberculin negative and for patients in this group to have less extensive active pulmonary disease. Although it is uncertain whether such associations result from a direct effect of vitamin D on protective immune reactions, the use of this vitamin as an adjunct to antituberculosis therapy merits consideration.