Age differences in allostatic load: an index of physiological dysregulation

Age differences in allostatic load: an index of physiological dysregulation
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DOI:
10.1016/s0531-5565(03)00099-8
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发表时间:
2003-07-01
影响因子:
3.9
通讯作者:
Seeman, T
Seeman, T
中科院分区:
医学2区
文献类型:
--
作者:
Crimmins, EM;Johnston, M;Seeman, T

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这份初步报告探讨了美国一个大的全国代表性人口的年龄在非稳态负荷的变化。它使用了来自20岁及以上美国人口的全国代表性样本的13项生理失调指标的数据。非稳态负荷在20 ~ 60岁急剧增加后,在老年阶段趋于稳定。我们假设这代表了生理状态对人群死亡率的选择性。(C)2003年爱思唯尔科学公司All rights reserved.
This preliminary report examines variation in allostatic load by age for a large nationally representative population of the United States. It uses data on 13 indicators of physiologic dysregulation from a nationally representative sample of the US population 20 years of age and over. Allostatic load is remarkably constant in the older ages after increasing sharply in the years from 20 to 60. We hypothesize that this represents mortality selectivity of the population by physiological status. (C) 2003 Elsevier Science Inc. All rights reserved.