Comparison of FP-7 and S-2 Ahmed glaucoma valve implantation in refractory glaucoma patients for short-term follow-up
Comparison of FP-7 and S-2 Ahmed glaucoma valve implantation in refractory glaucoma patients for short-term follow-up
复制标题
FP-7与S-2 Ahmed青光眼阀植入术用于难治性青光眼患者短期随访的比较
DOI：
10.3760/cma.j.issn.0366-6999.2011.08.002
复制
发表时间：
2011-04-20
影响因子：
6.1
通讯作者：
Zhuo Ye-hong
中科院分区：
文献类型：
--
作者：
Bai Yu-jing;Li Yi-qing;Zhuo Ye-hong
Background Ahmed glaucoma valves (AGV) has been used for decades, but there is no detailed report about the efficacy of AGV in Chinese glaucoma patients. This study aimed to compare the intraocular pressure (10P) lowering efficacy and side effects of S-2 polypropylene and PF-7 silicone AGV implantation in Chinese refractory glaucoma patients.Methods Patients were divided into S-2 model AGV group and FP-7 model AGV group. The complete and qualified surgical success rate, change of 10P, number of anti-glaucoma medications used and postoperative complications were recorded and analyzed.Results Average follow-up time was comparable between two groups. 10P was reduced from (37.9 +/- 12.7) mmHg preoperatively to (17.3 +/- 5.3) mmHg at the last follow-up in S-2 group and reduced from (39.9 +/- 14.4) mmHg to (17.7 +/- 4.9) mmHg in FP-7 group. Anti-glaucoma medications were reduced from 3.8 +/- 0.2 to 1.5 +/- 0.2 in S-2 group, and 3.5 +/- 0.2 to 0.7 +/- 0.2 in FP-7 groups. The cumulative success rates were comparable in two groups, which were 61.2% and 72.1% in S-2 group and FP-7 group respectively. When 10P reduction criteria was used, complete success rates were 30.6% and 51.2% for S-2 and FP-7 groups, and qualified success rates were 86.1% and 92.7% separately. In both groups, the major complication was hypotony, and the previous trabeculectomy of patients was the major risk factor for surgery failure.Conclusions In this short-term retrospective study, S-2 AGV is showed at least as effective as FP-7 AGV in 10P reduction, but associated with higher rate of complications. Previous trabeculectomy is a principle risk factor for AGV implantation failure. These clinical outcomes are important for converting use of the FP-7 silicon AGV in Chinese refractory glaucoma patients. Chin Med J 2011;124(8):1128-1133
